3JPR

Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-dimethyl methylene triphosphate

Summary for 3JPR

Related3JPN 3JPO 3JPP 3JPQ 3JPS 3JPT
DescriptorDNA polymerase beta, 5'-D(P*GP*TP*CP*GP*G)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3', ... (9 entities in total)
Functional Keywordsdna polymerase, transferase, stereoselectivity, halogenated analogs, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
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Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight48384.74
Authors
Batra, V.K.,Upton, J.,Kashmerov, B.,Beard, W.A.,Wilson, S.H.,Goodman, M.F.,McKenna, C.E. (deposition date: 2009-09-04, release date: 2010-06-02, Last modification date: 2011-07-13)
Primary citation
Batra, V.K.,Pedersen, L.C.,Beard, W.A.,Wilson, S.H.,Kashemirov, B.A.,Upton, T.G.,Goodman, M.F.,McKenna, C.E.
Halogenated beta,gamma-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase beta: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues.
J.Am.Chem.Soc., 132:7617-7625, 2010
PubMed: 20465217 (PDB entries with the same primary citation)
DOI: 10.1021/ja909370k
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253600.4%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution