PDB: 7770 件ウェブページステータス検索Chemie searchBIRD

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2ESA	GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA 分子名称: Endoplasmin, GELDANAMYCIN, TETRAETHYLENE GLYCOL, ... 著者 Immormino, R.M, Metzger IV, L.E, Gewirth, D.T. 登録日 2005-10-25 公開日 2006-10-03 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of GRP94 with the specific mutation KS168-169AA; with bound Geldanamycin To be Published
2FE8	SARS coronavirus papain-like protease: structure of a viral deubiquitinating enzyme 分子名称: BROMIDE ION, Replicase polyprotein 1ab, SULFATE ION, ... 著者 Ratia, K, Santarsiero, B.D, Mesecar, A.D. 登録日 2005-12-15 公開日 2006-03-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Severe acute respiratory syndrome coronavirus papain-like protease: Structure of a viral deubiquitinating enzyme Proc.Natl.Acad.Sci.Usa, 103, 2006
2F2T	Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.7 A resolution with 5-Aminoisoquinoline bound 分子名称: GLYCEROL, ISOQUINOLIN-5-AMINE, Nucleoside 2-deoxyribosyltransferase, ... 著者 Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2005-11-17 公開日 2005-11-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J.Med.Chem., 49, 2006
2FOL	Crystal structure of human RAB1A in complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-1A, ... 著者 Wang, J, Tempel, W, Shen, Y, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-01-13 公開日 2006-01-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.631 Å) 主引用文献 Crystal structure of human RAB1A in complex with GDP To be Published
2FZ2	Structure of Turnip Yellow Mosaic Virus at 100 K 分子名称: 5'-R(*CP*CP*C)-3', Coat protein 著者 Larson, S.B, Lucas, R.W, McPherson, A. 登録日 2006-02-08 公開日 2006-02-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The RNA of turnip yellow mosaic virus exhibits icosahedral order. Virology, 334, 2005
2FZ1	Structure of Empty Head Turnip Yellow Mosaic Virus (ATC) at 100 K 分子名称: Coat protein 著者 Larson, S.B, Lucas, R.W, McPherson, A. 登録日 2006-02-08 公開日 2006-02-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The RNA of turnip yellow mosaic virus exhibits icosahedral order. Virology, 334, 2005
2FV7	Crystal structure of human ribokinase 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribokinase, ... 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-01-30 公開日 2006-02-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human ribokinase to be published
2FWY	Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-H64 分子名称: 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE, Heat shock protein HSP 90-alpha 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-03 公開日 2006-10-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors. J.Med.Chem., 49, 2006
2FXS	Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide 分子名称: ATP-dependent molecular chaperone HSP82, GLYCEROL, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-06 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design. J.Mol.Biol., 388, 2009
2FYP	GRP94 in complex with the novel HSP90 Inhibitor Radester amine 分子名称: 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE, Endoplasmin, PENTAETHYLENE GLYCOL, ... 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-08 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Inhibittory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design To be Published
2G1L	Crystal structure of the FHA domain of human kinesin family member C 分子名称: CHLORIDE ION, Kinesin-like protein KIF1C, NICKEL (II) ION, ... 著者 Wang, J, Tempel, W, Shen, Y, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-02-14 公開日 2006-02-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Crystal structure of the FHA domain of human kinesin family member C to be published
2FWZ	Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-H71 分子名称: 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein HSP 90-alpha 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-03 公開日 2006-10-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors. J.Med.Chem., 49, 2006
5W1W	Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex 分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ... 著者 Gras, S, Walpole, N, Farenc, C, Rossjohn, J. 登録日 2017-06-05 公開日 2017-10-04 最終更新日 2018-01-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors. J. Biol. Chem., 292, 2017
5W61	Crystal structure of BAXP168G monomer co-crystallized with glycerol 分子名称: Apoptosis regulator BAX 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W60	Crystal structure of BAXP168G monomer cryo-protected with ethylene glycol 分子名称: Apoptosis regulator BAX, SULFATE ION 著者 Robin, A.Y, Colman, P.M, Czabotar, P.E. 登録日 2017-06-16 公開日 2018-06-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Ensemble Properties of Bax Determine Its Function. Structure, 26, 2018
5W3N	Molecular structure of FUS low sequence complexity domain protein fibrils 分子名称: RNA-binding protein FUS 著者 Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R. 登録日 2017-06-08 公開日 2017-09-27 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains. Cell, 171, 2017
2M5T	Solution structure of the 2A proteinase from a common cold agent, human rhinovirus RV-C02, strain W12 分子名称: ZINC ION, human rhinovirus 2A proteinase 著者 Lee, W, Frederick, R, Tonelli, M, Troupis, A.T, Reinin, N, Suchy, F.P, Moyer, K, Watters, K, Aceti, D, Palmenberg, A.C, Markley, J.L. 登録日 2013-03-07 公開日 2014-03-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2, Strain W12. Plos One, 9, 2014
5WDX	Structure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind and unwind viral RNA 分子名称: JFH-1 NS3, MAGNESIUM ION, ZINC ION 著者 Zhou, T, Pyle, A.M. 登録日 2017-07-06 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA. J. Virol., 92, 2018
2MBJ	Structure of an antiparallel (2+2) G-quadruplex formed by human telomeric repeats in Na+ solution (with G22-to-BrG substitution) 分子名称: DNA_(27-MER) 著者 Lim, K.W, Ng, V.C.M, Martin-Pintado, N, Heddi, B, Phan, A.T. 登録日 2013-08-02 公開日 2013-09-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity. Nucleic Acids Res., 41, 2013
5WOR	Corkscrew assembly of SOD1 residues 28-38 with familial mutation G37R 分子名称: GLYCEROL, MALONATE ION, Superoxide dismutase [Cu-Zn] 著者 Sangwan, S, Sawaya, M.R, Eisenberg, D.S. 登録日 2017-08-02 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Sci., 27, 2018
5WBG	Crystal Structure of human Cytochrome P450 2B6 (Y226H/K262R) in complex with an analog of a drug Efavirenz 分子名称: (2R,4S)-6-chloro-4-(cyclopropylethynyl)-2-methyl-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, 5-cyclohexylpentan-1-ol, ... 著者 Shah, M.B, Halpert, J.R. 登録日 2017-06-29 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog. Int J Mol Sci, 19, 2018
5WMJ	KVWGSI segment from Superoxide Dismutase 1,residues 30-35 分子名称: Superoxide dismutase [Cu-Zn], trifluoroacetic acid 著者 Sangwan, S, Sawaya, M, Eisenberg, D. 登録日 2017-07-28 公開日 2018-03-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations. Protein Sci., 27, 2018
5WOG	Human Hemoglobin immersed in Liquid Oxygen for 1 minute 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Gumpper, R.H, Terrell, J.R, Luo, M. 登録日 2017-08-02 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Hemoglobin crystals immersed in liquid oxygen reveal diffusion channels. Biochem. Biophys. Res. Commun., 495, 2018
5WC9	Human Pit-1 and 4xCATT DNA complex 分子名称: DNA (5'-D(*CP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*AP*TP*TP*CP*GP*GP*A)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*AP*AP*TP*GP*GP*T)-3'), Pituitary-specific positive transcription factor 1 著者 Agarwal, S, Cho, T.Y. 登録日 2017-06-29 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Biochemical and structural characterization of a novel cooperative binding mode by Pit-1 with CATT repeats in the macrophage migration inhibitory factor promoter. Nucleic Acids Res., 46, 2018
2MUZ	ssNMR structure of a designed rocker protein 分子名称: designed rocker protein 著者 Wang, T, Joh, N, Wu, Y, DeGrado, W.F, Hong, M. 登録日 2014-09-18 公開日 2014-12-24 最終更新日 2015-01-14 実験手法 SOLUTION NMR 主引用文献 De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014

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