5WDX

Structure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind and unwind viral RNA

Summary for 5WDX

• Entry DOI: 10.2210/pdb5wdx/pdb
• Descriptor: JFH-1 NS3, ZINC ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: viral replication, evolution, hepatitis c virus, enzymology, viral protein
• Biological source: Hepatitis C virus
• Total number of polymer chains: 1
• Total formula weight: 68956.21

Authors

Zhou, T.,Pyle, A.M. (deposition date: 2017-07-06, release date: 2017-11-08, Last modification date: 2023-10-04)

• Primary citation: Zhou, T.,Ren, X.,Adams, R.L.,Pyle, A.M.; NS3 from Hepatitis C Virus Strain JFH-1 Is an Unusually Robust Helicase That Is Primed To Bind and Unwind Viral RNA.; J. Virol., 92:-, 2018; PubMed: 29070684; DOI: 10.1128/JVI.01253-17

Experimental method

X-RAY DIFFRACTION (2.23 Å)