2ESA

GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA

Summary for 2ESA

• Entry DOI: 10.2210/pdb2esa/pdb
• Related: 1QY5 1TBW 1TC0 1TC6 1U2O 1YT1
• Descriptor: Endoplasmin, GELDANAMYCIN, TETRAETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: grp94 gp96 hsp90 bergerat chaperone endoplasmic reticulum geldanamycin 17-aag, chaperone
• Biological source: Canis lupus familiaris (dog); More
• Cellular location: Endoplasmic reticulum lumen: P41148
• Total number of polymer chains: 1
• Total formula weight: 27495.12

Authors

Immormino, R.M.,Metzger IV, L.E.,Gewirth, D.T. (deposition date: 2005-10-25, release date: 2006-10-03, Last modification date: 2023-08-23)

• Primary citation: Immormino, R.M.,Metzger IV, L.E.,Reardon, P.N.,Gewirth, D.T.; Crystal Structure of GRP94 with the specific mutation KS168-169AA; with bound Geldanamycin; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)