1S4J
 
 | | NMR structure of cross-reactive peptides from Homo sapiens | | 分子名称: | 60S acidic ribosomal protein P2 | | 著者 | Soares, M.R, Bisch, P.M, Campos de Carvalho, A.C, Valente, A.P, Almeida, F.C.L. | | 登録日 | 2004-01-16 | | 公開日 | 2004-03-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Correlation between conformation and antibody binding: NMR structure of cross-reactive peptides from T. cruzi, human and L. braziliensis
Febs Lett., 560, 2004
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7BXA
 | | Crystal structure of PD-1 in complex with tislelizumab Fab | | 分子名称: | Programmed cell death protein 1, heavy chain, light chain | | 著者 | Heo, Y.S, Lee, S.H, Lim, H, Lee, H.T, Kim, Y.J, Park, E.B. | | 登録日 | 2020-04-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy.
Biochem.Biophys.Res.Commun., 527, 2020
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8X0T
 | | Frizzled8 CRD in complex with pF8_AC3 Fab | | 分子名称: | Frizzled-8, pF8_AC3 Heavy chain, pF8_AC3 Light chain | | 著者 | Li, N, Ge, Q. | | 登録日 | 2023-11-06 | | 公開日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification and functional validation of FZD8-specific antibodies.
Int J Biol Macromol, 254, 2023
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6WZK
 | | LY3041658 Fab bound to CXCL3 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, C-X-C motif chemokine 3, ... | | 著者 | Durbin, J.D, Druzina, Z. | | 登録日 | 2020-05-14 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
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6WZL
 | | LY3041658 Fab bound to CXCL7 | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, C-X-C motif chemokine 7, LY3041658 Fab heavy chain, ... | | 著者 | Durbin, J.D, Druzina, Z. | | 登録日 | 2020-05-14 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
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6WZM
 | | LY3041658 Fab bound to CXCL8 | | 分子名称: | 1,2-ETHANEDIOL, Interleukin-8, LY3041658 Fab heavy chain, ... | | 著者 | Durbin, J.D, Druzina, Z. | | 登録日 | 2020-05-14 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
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6WZJ
 | | LY3041658 Fab bound to CXCL2 | | 分子名称: | C-X-C motif chemokine 2, LY3041658 Fab Heavy Chain, LY3041658 Fab Light Chain | | 著者 | Durbin, J.D, Druzina, Z. | | 登録日 | 2020-05-14 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
Mabs, 12
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6XKR
 | | Structure of Sasanlimab Fab in complex with PD-1 | | 分子名称: | GLYCEROL, Programmed cell death protein 1, Sasanlimab Fab Heavy chain, ... | | 著者 | Kimberlin, C.R, Chin, S.M. | | 登録日 | 2020-06-27 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody.
Mol.Cancer Ther., 19, 2020
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7UGM
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6X8S
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6U0N
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6X8Q
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6X8U
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6OPA
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6X8P
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6U0L
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6NOV
 | | A Fab derived from ixekizumab | | 分子名称: | DODECAETHYLENE GLYCOL, Fab Heavy Chain, Fab Light Chain | | 著者 | Durbin, J.D, Clawson, D.K, Lu, F, Tian, Y, Lu, J, Schmitt, M, Atwell, S. | | 登録日 | 2019-01-16 | | 公開日 | 2019-06-19 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease.
Mabs, 11, 2019
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6OO0
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6P4B
 | | HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S) | | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ... | | 著者 | Langley, D.B, Christ, D. | | 登録日 | 2019-05-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6OZ9
 | | Ebola virus glycoprotein in complex with EBOV-520 Fab | | 分子名称: | EBOV-520 Fab heavy chain, EBOV-520 Fab light chain, Envelope glycoprotein, ... | | 著者 | Milligan, J.C, Altman, P.X, Hui, S, Hastie, K.M, Gilchuk, P, Crowe, J.E, Saphire, E.O. | | 登録日 | 2019-05-15 | | 公開日 | 2020-03-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.462 Å) | | 主引用文献 | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.
Immunity, 52, 2020
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6P4A
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8FM0
 | | HIV-1 gp120 complex with CJF-III-214 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, methyl (2R,3S)-2-(carbamimidamidomethyl)-3-[2-(4-chloro-3-fluoroanilino)(oxo)acetamido]-6-[(methylamino)methyl]-2,3-dihydro-1H-indole-1-carboxylate | | 著者 | Gong, Z, Hendrickson, W.A. | | 登録日 | 2022-12-22 | | 公開日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8FM4
 | | HIV-1 gp120 complex with CJF-IV-047 | | 分子名称: | 2,2,2-trifluoroethyl (2R,3S)-2-(carbamimidamidomethyl)-3-[2-(4-chloro-3-fluoroanilino)(oxo)acetamido]-6-[(methylamino)methyl]-2,3-dihydro-1H-indole-1-carboxylate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120 | | 著者 | Gong, Z, Hendrickson, W.A. | | 登録日 | 2022-12-22 | | 公開日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8FLZ
 | | HIV-1 gp120 complex with CJF-III-049-S | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3S)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide | | 著者 | Gong, Z, Hendrickson, W.A. | | 登録日 | 2022-12-22 | | 公開日 | 2023-04-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6FLA
 | | 3H5 Fab bound to EDIII of DenV 2 Xtal form 1 | | 分子名称: | CHLORIDE ION, Domain III of Dengue virus 2, GLYCEROL, ... | | 著者 | Flanagan, A, Renner, M, Grimes, J.M. | | 登録日 | 2018-01-25 | | 公開日 | 2018-10-24 | | 最終更新日 | 2019-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.
Nat. Immunol., 19, 2018
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