7BXA
Crystal structure of PD-1 in complex with tislelizumab Fab
Summary for 7BXA
Entry DOI | 10.2210/pdb7bxa/pdb |
Descriptor | Programmed cell death protein 1, heavy chain, light chain (3 entities in total) |
Functional Keywords | pd-1, tislelizumab, immune checkpoint, antibody, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 126092.27 |
Authors | |
Primary citation | Lee, S.H.,Lee, H.T.,Lim, H.,Kim, Y.,Park, U.B.,Heo, Y.S. Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy. Biochem.Biophys.Res.Commun., 527:226-231, 2020 Cited by PubMed: 32446372DOI: 10.1016/j.bbrc.2020.04.121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.32 Å) |
Structure validation
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