7BXA
Crystal structure of PD-1 in complex with tislelizumab Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, P | Programmed cell death protein 1 | polymer | 130 | 14855.5 | 2 | UniProt (Q15116) Pfam (PF07686) In PDB | Homo sapiens (Human) | hPD-1 |
2 | B, H | heavy chain | polymer | 230 | 24641.6 | 2 | Homo sapiens | ||
3 | C, L | light chain | polymer | 214 | 23549.1 | 2 | Homo sapiens |
Sequence modifications
A, P: 29 - 150 (UniProt: Q15116)
PDB | External Database | Details |
---|---|---|
Ser 93 | Cys 93 | engineered mutation |
Leu 151 | - | expression tag |
Glu 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
His 156 | - | expression tag |
His 157 | - | expression tag |
His 158 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 126092.3 | |
All* | Total formula weight | 126092.3 |