7BXA

Crystal structure of PD-1 in complex with tislelizumab Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, P)	Programmed cell death protein 1	polymer	130	14855.5	2	UniProt (Q15116) Pfam (PF07686)	Homo sapiens (Human)	hPD-1
2	B, E (B, H)	heavy chain	polymer	230	24641.6	2		Homo sapiens
3	C, F (C, L)	light chain	polymer	214	23549.1	2		Homo sapiens

Sequence modifications

A, P: 29 - 150 (UniProt: Q15116)

PDB	External Database	Details
Ser 93	Cys 93	engineered mutation
Leu 151	-	expression tag
Glu 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	126092.3
All*	Total formula weight	126092.3

*Water molecules are not included.