7Y58
 
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4R86
 | | Crystal Structure of Aminoglycoside/Multidrug Efflux System AcrD from Salmonella typhimurium | | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, Y, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-08-29 | | 公開日 | 2014-10-08 | | 最終更新日 | 2016-10-12 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Crystal Structure of Aminoglycoside/Multidrug Efflux System AcrD from
Salmonella typhimurium
To be Published
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4Z3P
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4Z3N
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5C6N
 | | protein A | | 分子名称: | BH2163 protein | | 著者 | Lu, M. | | 登録日 | 2015-06-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps.
Nat Commun, 6, 2015
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5C6P
 | | protein C | | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D | | 著者 | Lu, M. | | 登録日 | 2015-06-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps.
Nat Commun, 6, 2015
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5C6O
 | | protein B | | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, BH2163 protein | | 著者 | Lu, M. | | 登録日 | 2015-06-23 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps.
Nat Commun, 6, 2015
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8SX8
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8SXB
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8SX7
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8IZR
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8IZP
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6IOK
 | | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | | 分子名称: | Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM | | 著者 | Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2019-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Nat Commun, 10, 2019
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6IOL
 | | Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) | | 分子名称: | Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM | | 著者 | Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. | | 登録日 | 2018-10-30 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Nat Commun, 10, 2019
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5T0O
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1EXJ
 | | CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPP | | 分子名称: | DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, SODIUM ION, ... | | 著者 | Zheleznova-Heldwein, E.E, Brennan, R.G. | | 登録日 | 2000-05-02 | | 公開日 | 2001-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Nature, 409, 2001
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1EXI
 | | CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPSB | | 分子名称: | DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, TETRAPHENYLANTIMONIUM ION, ... | | 著者 | Zheleznova-Heldwein, E.E, Brennan, R.G. | | 登録日 | 2000-05-02 | | 公開日 | 2001-01-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | Crystal structure of the transcription activator BmrR bound to DNA and a drug.
Nature, 409, 2001
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7CZ9
 | | Crystal structure of multidrug efflux transporter OqxB from Klebsiella pneumoniae | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter, GLYCEROL, ... | | 著者 | Murakami, S, Okada, U, Yamashita, E. | | 登録日 | 2020-09-07 | | 公開日 | 2021-09-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae.
Nat Commun, 12, 2021
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5AZS
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4CDI
 | | Crystal structure of AcrB-AcrZ complex | | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN | | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | | 登録日 | 2013-10-31 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structure of the Acrab-Tolc Multidrug Efflux Pump.
Nature, 509, 2014
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4C48
 | | Crystal structure of AcrB-AcrZ complex | | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | | 登録日 | 2013-09-02 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the AcrAB-TolC multidrug efflux pump.
Nature, 509, 2014
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2W1B
 | | The structure of the efflux pump AcrB in complex with bile acid | | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B | | 著者 | Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. | | 登録日 | 2008-10-17 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | | 主引用文献 | The Structure of the Efflux Pump Acrb in Complex with Bile Acid.
Mol.Membr.Biol., 25, 2008
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8WI2
 | | RD-hMRP5-inward open | | 分子名称: | ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER | | 著者 | Liu, Z.M, Huang, Y. | | 登録日 | 2023-09-24 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
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8WI3
 | | ND-hMRP5-inward open | | 分子名称: | ATP-binding cassette sub-family C member 5 | | 著者 | Liu, Z.M, Huang, Y. | | 登録日 | 2023-09-24 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
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8WI0
 | | wt-hMRP5 inward-open | | 分子名称: | ATP-binding cassette sub-family C member 5 | | 著者 | Liu, Z.M, Huang, Y. | | 登録日 | 2023-09-24 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
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