7Y58
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4R86
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![BU of 4r86 by Molmil](/molmil-images/mine/4r86) | Crystal Structure of Aminoglycoside/Multidrug Efflux System AcrD from Salmonella typhimurium | 分子名称: | 1,2-ETHANEDIOL, BROMIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kim, Y, Maltseva, N, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2014-08-29 | 公開日 | 2014-10-08 | 最終更新日 | 2016-10-12 | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | 主引用文献 | Crystal Structure of Aminoglycoside/Multidrug Efflux System AcrD from
Salmonella typhimurium To be Published
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4Z3P
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4Z3N
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5C6N
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![BU of 5c6n by Molmil](/molmil-images/mine/5c6n) | protein A | 分子名称: | BH2163 protein | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6P
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![BU of 5c6p by Molmil](/molmil-images/mine/5c6p) | protein C | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6O
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![BU of 5c6o by Molmil](/molmil-images/mine/5c6o) | protein B | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, BH2163 protein | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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8SX8
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8SXB
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8SX7
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8IZR
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8IZP
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6IOK
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![BU of 6iok by Molmil](/molmil-images/mine/6iok) | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | 分子名称: | Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM | 著者 | Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. | 登録日 | 2018-10-30 | 公開日 | 2019-04-03 | 最終更新日 | 2019-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | 主引用文献 | Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
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6IOL
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![BU of 6iol by Molmil](/molmil-images/mine/6iol) | Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) | 分子名称: | Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM | 著者 | Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. | 登録日 | 2018-10-30 | 公開日 | 2019-04-03 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
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5T0O
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1EXJ
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![BU of 1exj by Molmil](/molmil-images/mine/1exj) | CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPP | 分子名称: | DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, SODIUM ION, ... | 著者 | Zheleznova-Heldwein, E.E, Brennan, R.G. | 登録日 | 2000-05-02 | 公開日 | 2001-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature, 409, 2001
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1EXI
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![BU of 1exi by Molmil](/molmil-images/mine/1exi) | CRYSTAL STRUCTURE OF TRANSCRIPTION ACTIVATOR BMRR, FROM B. SUBTILIS, BOUND TO 21 BASE PAIR BMR OPERATOR AND TPSB | 分子名称: | DNA (5'-D(*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*T)-3'), MULTIDRUG-EFFLUX TRANSPORTER REGULATOR, TETRAPHENYLANTIMONIUM ION, ... | 著者 | Zheleznova-Heldwein, E.E, Brennan, R.G. | 登録日 | 2000-05-02 | 公開日 | 2001-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature, 409, 2001
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7CZ9
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![BU of 7cz9 by Molmil](/molmil-images/mine/7cz9) | Crystal structure of multidrug efflux transporter OqxB from Klebsiella pneumoniae | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Efflux pump membrane transporter, GLYCEROL, ... | 著者 | Murakami, S, Okada, U, Yamashita, E. | 登録日 | 2020-09-07 | 公開日 | 2021-09-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae. Nat Commun, 12, 2021
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5AZS
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4CDI
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![BU of 4cdi by Molmil](/molmil-images/mine/4cdi) | Crystal structure of AcrB-AcrZ complex | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | 登録日 | 2013-10-31 | 公開日 | 2014-04-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure of the Acrab-Tolc Multidrug Efflux Pump. Nature, 509, 2014
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4C48
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![BU of 4c48 by Molmil](/molmil-images/mine/4c48) | Crystal structure of AcrB-AcrZ complex | 分子名称: | ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Du, D, James, N, Klimont, E, Luisi, B.F. | 登録日 | 2013-09-02 | 公開日 | 2014-04-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the AcrAB-TolC multidrug efflux pump. Nature, 509, 2014
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2W1B
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![BU of 2w1b by Molmil](/molmil-images/mine/2w1b) | The structure of the efflux pump AcrB in complex with bile acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B | 著者 | Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K. | 登録日 | 2008-10-17 | 公開日 | 2008-12-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.85 Å) | 主引用文献 | The Structure of the Efflux Pump Acrb in Complex with Bile Acid. Mol.Membr.Biol., 25, 2008
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8WI2
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![BU of 8wi2 by Molmil](/molmil-images/mine/8wi2) | RD-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.06 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI3
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![BU of 8wi3 by Molmil](/molmil-images/mine/8wi3) | ND-hMRP5-inward open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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8WI0
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![BU of 8wi0 by Molmil](/molmil-images/mine/8wi0) | wt-hMRP5 inward-open | 分子名称: | ATP-binding cassette sub-family C member 5 | 著者 | Liu, Z.M, Huang, Y. | 登録日 | 2023-09-24 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Inhibition and transport mechanisms of the ABC transporter hMRP5. Nat Commun, 15, 2024
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