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2PX8
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Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH and 7M-GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ...
著者Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF)
登録日2007-05-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PXC
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Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAM and GTPA
分子名称: GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYLMETHIONINE
著者Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF)
登録日2007-05-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PXA
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Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH and GTPG
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYL-L-HOMOCYSTEINE
著者Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF)
登録日2007-05-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2PX2
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Crystal structure of the Murray Valley Encephalitis Virus NS5 2'-O Methyltransferase domain in complex with SAH (Monoclinic form 1)
分子名称: CHLORIDE ION, Genome polyprotein [Contains: Capsid protein C (Core protein); Envelope protein M (Matrix protein); Major envelope protein E; Non-structural protein 1 (NS1); Non-structural protein 2A (NS2A); Flavivirin protease NS2B regulatory subunit; Flavivirin protease NS3 catalytic subunit; Non-structural protein 4A (NS4A); Non-structural protein 4B (NS4B); RNA-directed RNA polymerase (EC 2.7.7.48) (NS5)], S-ADENOSYL-L-HOMOCYSTEINE
著者Assenberg, R, Ren, J, Verma, A, Walter, T.S, Alderton, D, Hurrelbrink, R.J, Fuller, S.D, Owens, R.J, Stuart, D.I, Grimes, J.M, Oxford Protein Production Facility (OPPF)
登録日2007-05-14
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the Murray Valley encephalitis virus NS5 methyltransferase domain in complex with cap analogues.
J.Gen.Virol., 88, 2007
2JQM
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Yellow Fever Envelope Protein Domain III NMR Structure (S288-K398)
分子名称: Envelope protein E
著者Volk, D.E, Gandham, S.H, May, F.J, Anderson, A, Barrett, A.D, Gorenstein, D.G.
登録日2007-06-03
公開日2008-06-10
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structure of yellow fever virus envelope protein domain III.
Virology, 394, 2009
2QE2
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Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor
分子名称: 2-{[N-(2-ACETYL-5-CHLORO-4-FLUOROPHENYL)GLYCYL]AMINO}BENZOIC ACID, RNA-directed RNA polymerase
著者Chopra, R, Svenson, K, Bard, J.
登録日2007-06-22
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Anthranilic Acid Derivatives as a Novel Class of Allosteric Inhibitors of Hepatitis C NS5B Polymerase
J.Med.Chem., 50, 2007
2QE5
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Structure of HCV NS5B Bound to an Anthranilic Acid Inhibitor
分子名称: 2-{[(4-CHLOROPHENOXY)ACETYL]AMINO}BENZOIC ACID, RNA-directed RNA polymerase
著者Chopra, R, Svenson, K, Bard, J.
登録日2007-06-22
公開日2007-10-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of Anthranilic Acid Derivatives as a Novel Class of Allosteric Inhibitors of Hepatitis C NS5B Polymerase
J.Med.Chem., 50, 2007
2QEQ
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Crystal structure of kunjin virus ns3 helicase
分子名称: Flavivirin protease NS3 catalytic subunit
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2007-06-26
公開日2007-08-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein
J.Mol.Biol., 372, 2007
2QJ1
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Crystal structure of infectious bursal disease virus VP1 polymerase incubated with an oligopeptide mimicking the VP3 C-terminus
分子名称: Infectious bursal disease virus VP1 polymerase
著者Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N.
登録日2007-07-06
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase
To be Published
2V6I
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Kokobera Virus Helicase
分子名称: PYROPHOSPHATE 2-, RNA HELICASE
著者Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A.
登録日2007-07-18
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V6J
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Kokobera Virus Helicase: Mutant Met47Thr
分子名称: RNA HELICASE
著者Speroni, S, De Colibus, L, Coutard, B, Canard, B, Mattevi, A.
登録日2007-07-18
公開日2008-03-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and Biochemical Analysis of Kokobera Virus Helicase
Proteins: Struct., Funct., Bioinf., 70, 2008
2V8O
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Structure of the Murray Valley encephalitis virus RNA helicase to 1. 9A resolution
分子名称: FLAVIVIRIN PROTEASE NS3
著者Mancini, E.J, Assenberg, R, Verma, A, Walter, T.S, Tuma, R, Grimes, J.M, Owens, R.J, Stuart, D.I.
登録日2007-08-09
公開日2007-08-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Murray Valley Encephalitis Virus RNA Helicase at 1.9 A Resolution.
Protein Sci., 16, 2007
2R18
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Structural insights into the multifunctional protein VP3 of Birnaviruses
分子名称: Capsid assembly protein VP3
著者Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N.
登録日2007-08-22
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
2Z7J
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Structural insights into de multifunctional VP3 protein of birnaviruses:gold derivative
分子名称: Capsid assembly protein VP3, GOLD ION
著者Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N.
登録日2007-08-23
公開日2008-02-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into the multifunctional protein VP3 of birnaviruses.
Structure, 16, 2008
2R29
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Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
分子名称: Envelope protein E, Heavy chain of Fab 1A1D-2, Light chain of Fab 1A1D-2
著者Lok, S.M, Kostyuchenko, V.K, Nybakken, G.E, Holdaway, H.A, Battisti, A.J, Sukupolvi-petty, S, Sedlak, D, Fremont, D.H, Chipman, P.R, Roehrig, J.T, Diamond, M.S, Kuhn, R.J, Rossmann, M.G.
登録日2007-08-24
公開日2007-12-25
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
2R70
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Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.
分子名称: INFECTIOUS BURSAL VIRUS VP1 POLYMERASE
著者Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N.
登録日2007-09-07
公開日2007-11-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R72
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Crystal structure of infectious bursal disease virus VP1 polymerase, incubated with Mg2+ ion.
分子名称: INFECTIOUS BURSAL DISEASE VIRUS VP1 POLYMERASE, MAGNESIUM ION
著者Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N.
登録日2007-09-07
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R7Q
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Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (C-terminal hexahistidine-tagged)
分子名称: RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7R
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC) complex
分子名称: RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7O
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Crystal Structure of VP1 apoenzyme of Rotavirus SA11 (N-terminal hexahistidine-tagged)
分子名称: RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-09
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7U
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Crystal Structure of Rotavirus SA11 VP1/RNA (AAAAGCC) Complex
分子名称: RNA (5'-R(*AP*A*AP*AP*GP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7X
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/GTP complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7W
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGACC)/mRNA 5'-CAP (m7GpppG) complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA (5'-R(*UP*GP*UP*GP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008
2R7Z
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Cisplatin lesion containing RNA polymerase II elongation complex
分子名称: 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ...
著者Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P.
登録日2007-09-10
公開日2007-11-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Mechanism of transcriptional stalling at cisplatin-damaged DNA.
Nat.Struct.Mol.Biol., 14, 2007
2R7T
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Crystal Structure of Rotavirus SA11 VP1/RNA (UGUGAACC) Complex
分子名称: RNA (5'-R(*UP*GP*UP*GP*AP*AP*CP*C)-3'), RNA-dependent RNA polymerase
著者Lu, X, Harrison, S.C, Tao, Y.J, Patton, J.T, Nibert, M.L.
登録日2007-09-10
公開日2008-07-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism for coordinated RNA packaging and genome replication by rotavirus polymerase VP1.
Structure, 16, 2008

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