6QNX
| Structure of the SA2/SCC1/CTCF complex | 分子名称: | Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, Transcriptional repressor CTCF | 著者 | Li, Y, Muir, K.W, Panne, D. | 登録日 | 2019-02-12 | 公開日 | 2020-01-22 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The structural basis for cohesin-CTCF-anchored loops. Nature, 578, 2020
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8RQC
| Crystal structure of CRBN-midi in complex with mezigdomide and IKZF1 ZF2 | 分子名称: | DNA-binding protein Ikaros, Mezigdomide, Protein cereblon, ... | 著者 | Furihata, H, Kroupova, A, Zollman, D, Ciulli, A. | 登録日 | 2024-01-17 | 公開日 | 2024-09-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders To Be Published
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7YSF
| Crystal structure of ZNF524 ZF1-4 in complex with telomeric DNA | 分子名称: | D-MALATE, DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*C)-3'), ... | 著者 | Li, F.D, Xu, Z.Y. | 登録日 | 2022-08-12 | 公開日 | 2023-08-16 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | ZNF524 directly interacts with telomeric DNA and supports telomere integrity. Nat Commun, 14, 2023
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8U16
| The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-short bound to Pomalidomide | 分子名称: | 1,2-ETHANEDIOL, DNA damage-binding protein 1, Protein cereblon, ... | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | 登録日 | 2023-08-30 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
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8U17
| The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-long bound to Pomalidomide | 分子名称: | DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | 登録日 | 2023-08-30 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
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8U15
| The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-short bound to CC-220 | 分子名称: | (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DDB1, Protein cereblon, ... | 著者 | Clifton, M.C, Ma, X, Ornelas, E. | 登録日 | 2023-08-30 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
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8TNR
| Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 2 | 分子名称: | 2-[(3S)-2,6-dioxopiperidin-3-yl]-5-(morpholin-4-yl)-1H-isoindole-1,3(2H)-dione, DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, ... | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | 登録日 | 2023-08-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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8TNP
| Cryo-EM structure of DDB1dB:CRBN:Pomalidomide:SD40 | 分子名称: | DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, Protein cereblon, ... | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | 登録日 | 2023-08-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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8TNQ
| Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 1 | 分子名称: | 2-[(3S)-2,6-dioxopiperidin-3-yl]-5-(morpholin-4-yl)-1H-isoindole-1,3(2H)-dione, DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, ... | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | 登録日 | 2023-08-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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2RV6
| Solution structures of the DNA-binding domains (ZF2-ZF3-ZF4) of immune-related zinc-finger protein ZFAT | 分子名称: | ZINC ION, Zinc finger protein ZFAT | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | 登録日 | 2015-01-26 | 公開日 | 2015-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT J.Struct.Funct.Genom., 16, 2015
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2RSJ
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2RPC
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2HGH
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2J7J
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1TF6
| CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*GP*CP*CP*TP*GP*GP*TP*TP*AP*GP*TP*AP*C P*CP*TP*GP*GP*AP* TP*GP*GP*GP*AP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*AP*GP*GP*T P*AP*CP*TP*AP*AP* CP*CP*AP*GP*GP*CP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR IIIA), ... | 著者 | Nolte, R.T, Conlin, R.M, Harrison, S.C, Brown, R.S. | 登録日 | 1998-03-02 | 公開日 | 1998-07-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proc.Natl.Acad.Sci.USA, 95, 1998
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1UN6
| THE CRYSTAL STRUCTURE OF A ZINC FINGER - RNA COMPLEX REVEALS TWO MODES OF MOLECULAR RECOGNITION | 分子名称: | 5S RIBOSOMAL RNA, MAGNESIUM ION, TRANSCRIPTION FACTOR IIIA, ... | 著者 | Lu, D, Searles, M.A, Klug, A. | 登録日 | 2003-09-04 | 公開日 | 2003-11-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal Structure of a Zinc-Finger-RNA Complex Reveals Two Modes of Molecular Recognition Nature, 426, 2003
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2LVU
| Solution structure of Miz-1 zinc finger 10 | 分子名称: | ZINC ION, Zinc finger and BTB domain-containing protein 17 | 著者 | Bedard, M, Maltais, L, Beaulieu, M, Bernard, D, Lavigne, P. | 登録日 | 2012-07-11 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10. J.Biomol.Nmr, 54, 2012
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2LVR
| Solution structure of Miz-1 zinc finger 8 | 分子名称: | ZINC ION, Zinc finger and BTB domain-containing protein 17 | 著者 | Bedard, M, Maltais, L, Beaulieu, M, Bernard, D, Lavigne, P. | 登録日 | 2012-07-10 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10. J.Biomol.Nmr, 54, 2012
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2LVT
| Solution structure of Miz-1 zinc finger 9 | 分子名称: | ZINC ION, Zinc finger and BTB domain-containing protein 17 | 著者 | Bedard, M, Maltais, L, Beaulieu, M, Bernard, D, Lavigne, P. | 登録日 | 2012-07-11 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure note: solution structure of human Miz-1 zinc fingers 8 to 10. J.Biomol.Nmr, 54, 2012
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2M0F
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2M0E
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2M0D
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