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7AHQ
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BU of 7ahq by Molmil
Cryo-EM structure of F-actin stabilized by trans-optoJASP-8
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Pospich, S, Raunser, S.
登録日2020-09-25
公開日2021-01-27
最終更新日2021-04-14
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM Resolves Molecular Recognition Of An Optojasp Photoswitch Bound To Actin Filaments In Both Switch States.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KEN
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BU of 7ken by Molmil
Protein Tyrosine Phosphatase 1B, D289A mutant, apo state
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Fox, J.M, Hongdusit, A.
登録日2020-10-11
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Optogenetic Analysis of Allosteric Control in Protein Tyrosine Phosphatases.
Biochemistry, 60, 2021
7L1X
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BU of 7l1x by Molmil
Structure of human CK2 alpha kinase (catalytic subunit) with the inhibitor 108600.
分子名称: (2~{Z})-6-[[2,6-bis(chloranyl)phenyl]methylsulfonyl]-2-[[4-oxidanyl-3-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]methylidene]-4~{H}-1,4-benzothiazin-3-one, Casein kinase II subunit alpha, GLYCEROL, ...
著者Rechkoblit, O, Aggarwal, A.K.
登録日2020-12-15
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease.
Nat Commun, 12, 2021
7DVV
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BU of 7dvv by Molmil
Heme sensor protein PefR from Streptococcus agalactiae bound to operator DNA (28-mer)
分子名称: DNA (28-MER), HTH marR-type domain-containing protein
著者Nishinaga, M, Nagai, S, Nishitani, Y, Sugimoto, H, Shiro, Y, Sawai, H.
登録日2021-01-15
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival.
Commun Biol, 4, 2021
7BL1
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BU of 7bl1 by Molmil
human complex II-BATS bound to membrane-attached Rab5a-GTP
分子名称: Beclin-1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Tremel, S, Morado, D.R, Kovtun, O, Williams, R.L, Briggs, J.A.G, Munro, S, Ohashi, Y, Bertram, J, Perisic, O.
登録日2021-01-17
公開日2021-03-03
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
Nat Commun, 12, 2021
7EMN
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BU of 7emn by Molmil
The atomic structure of SHP2 E76A mutant
分子名称: Tyrosine-protein phosphatase non-receptor type 11
著者Luo, F, Xie, J.J, Zhu, J.D, Liu, C.
登録日2021-04-14
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism.
J.Biol.Chem., 296, 2021
7P9T
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BU of 7p9t by Molmil
Crystal structure of CD73 in complex with dCMP in the open form
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-nucleotidase, CALCIUM ION, ...
著者Scaletti, E.R, Strater, N.
登録日2021-07-27
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives.
Purinergic Signal, 17, 2021
7VW9
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BU of 7vw9 by Molmil
Helicoverpa armigera pheromone-binding protein PBP1 at pH 5.5
分子名称: PBP1
著者Zheng, J, Chen, Z.
登録日2021-11-10
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Insights into the Ligand-Binding and -Releasing Mechanism of Helicoverpa armigera Pheromone-Binding Protein PBP1.
Int J Mol Sci, 23, 2022
7QHS
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BU of 7qhs by Molmil
S. cerevisiae CMGE nucleating origin DNA melting
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ...
著者Lewis, J.S, Sousa, J.S, Costa, A.
登録日2021-12-14
公開日2022-06-15
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of replication origin melting nucleated by CMG helicase assembly.
Nature, 606, 2022
7X6G
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BU of 7x6g by Molmil
Outer membrane lipoprotein QseG of Escherichia coli O157:H7
分子名称: Quorum-sensing regulator protein G
著者Matsumoto, K, Fukuda, Y, Inoue, T.
登録日2022-03-07
公開日2023-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
7X6H
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BU of 7x6h by Molmil
Outer membrane lipoprotein QseG of Escherichia coli O157:H7
分子名称: Quorum-sensing regulator protein G
著者Matsumoto, K, Fukuda, Y, Inoue, T.
登録日2022-03-07
公開日2023-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
7X6F
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BU of 7x6f by Molmil
Outer membrane lipoprotein QseG of Escherichia coli O157:H7
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CITRATE ANION, ...
著者Matsumoto, K, Fukuda, Y, Inoue, T.
登録日2022-03-07
公開日2023-03-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli.
Acta Crystallogr.,Sect.F, 79, 2023
8AAF
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BU of 8aaf by Molmil
Yeast RQC complex in state G
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-01
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGT
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BU of 8agt by Molmil
Yeast RQC complex in state F
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGZ
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BU of 8agz by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGV
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BU of 8agv by Molmil
Yeast RQC complex in state H
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGW
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BU of 8agw by Molmil
Yeast RQC complex in state D
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGX
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BU of 8agx by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the IN position
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGU
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BU of 8agu by Molmil
Yeast RQC complex in state E
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8EMQ
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BU of 8emq by Molmil
Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera.
分子名称: FE (III) ION, Ferritin heavy chain, N-terminally processed, ...
著者Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M.
登録日2022-09-28
公開日2022-12-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (1.66 Å)
主引用文献Characterizing the resolution and throughput of the Apollo direct electron detector.
J Struct Biol X, 7, 2023
8EN7
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BU of 8en7 by Molmil
Mouse apoferritin heavy chain without zinc determined using single-particle cryo-EM with Apollo camera.
分子名称: FE (III) ION, Ferritin heavy chain, N-terminally processed
著者Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M.
登録日2022-09-28
公開日2022-12-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (1.68 Å)
主引用文献Characterizing the resolution and throughput of the Apollo direct electron detector.
J Struct Biol X, 7, 2023
8STN
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BU of 8stn by Molmil
Crystal structure of KRAS-G12D/G75A mutant, GDP-bound
分子名称: CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tran, T.H, Dharmaiah, S, Simanshu, D.K.
登録日2023-05-10
公開日2023-08-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
8STM
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BU of 8stm by Molmil
Crystal structure of KRAS-G75A mutant, GDP-bound
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Tran, T.H, Dharmaiah, S, Simanshu, D.K.
登録日2023-05-10
公開日2023-08-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity.
Cancer Res., 83, 2023
8R7Y
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BU of 8r7y by Molmil
Deoxyribonucleoside regulator DeoR in complex with the DNA operator
分子名称: Deoxyribonucleoside regulator, OL18 DNA operator, strand 1, ...
著者Pachl, P, Soltysova, M, Rezacova, P.
登録日2023-11-27
公開日2024-06-19
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function.
Nucleic Acids Res., 2024
8R9R
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BU of 8r9r by Molmil
GDP-bound state of S. putrefaciens FlhF
分子名称: Flagellar biosynthesis protein FlhF, GUANOSINE-5'-DIPHOSPHATE
著者Mais, C.N, Dornes, A, Bange, G.
登録日2023-11-30
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structure of the GDP-bound state of the SRP GTPase FlhF.
Acta Crystallogr.,Sect.F, 80, 2024

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件を2024-06-26に公開中

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