PDB: 47011 件ウェブページステータス検索Chemie searchBIRD

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8B9A	S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. 分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... 著者 Jones, M.L, Yeeles, J.T.P. 登録日 2022-10-05 公開日 2023-08-09 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
9GEF	Experimental localization of metal-binding sites reveals the role of metal ions in the delafloxacin-stabilized Streptococcus pneumoniae topoisomerase IV DNA cleavage complex 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Wang, B, Najmudin, S, Pan, X.-S, Mykhaylyk, V, Orr, C, Wagner, A, Govada, L, Chayen, N.E, Fisher, L.M, Sanderson, M.R. 登録日 2024-08-08 公開日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Experimental localization of metal-binding sites reveals the role of metal ions in type II DNA topoisomerases. Proc.Natl.Acad.Sci.USA, 121, 2024
9F6I	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state) 分子名称: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6L	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state) 分子名称: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
1FOS	TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES 分子名称: C-JUN PROTO-ONCOGENE PROTEIN, DNA (5'-D(*AP*AP*TP*GP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*AP*GP*GP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*CP*CP*TP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*CP*AP*T)-3'), ... 著者 Glover, J.N.M, Harrison, S.C. 登録日 1995-03-07 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal structure of the heterodimeric bZIP transcription factor c-Fos-c-Jun bound to DNA. Nature, 373, 1995
9BDY	AT-centric NF-kappaB RelA binding DNA 分子名称: ACETATE ION, DNA (5'-D(*CP*GP*GP*AP*AP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*G)-3'), ... 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. 登録日 2024-04-13 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
3N4M	E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ... 著者 Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L. 登録日 2010-05-21 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry, 59, 2020
9BE0	GC-centric NF-kappaB RelA binding DNA 分子名称: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*GP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*CP*TP*TP*CP*CP*CP*G)-3'), ZINC ION 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Ghosh, G. 登録日 2024-04-13 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
3M3Y	RNA polymerase II elongation complex C 分子名称: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Zhu, G, Huang, X, Lippard, S.J. 登録日 2010-03-10 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
3M4O	RNA polymerase II elongation complex B 分子名称: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Zhu, G, Huang, X, Lippard, S.J. 登録日 2010-03-11 公開日 2010-05-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
9BDZ	TA-centric NF-kappaB RelA binding DNA 分子名称: ACETATE ION, ZINC ION, double-stranded DNA 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. 登録日 2024-04-13 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
8YHA	Type I-EHNH Cascade-ssDNA complex 分子名称: 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... 著者 Li, Z. 登録日 2024-02-27 公開日 2024-07-31 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems. Mol.Cell, 84, 2024
9BE1	CG-centric NF-kappaB RelA binding DNA 分子名称: ACETATE ION, DNA (5'-D(*CP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*G)-3'), ZINC ION 著者 Biswas, T, Shahabi, S, Tsodikov, O.V, Wang, V, Ghosh, G. 登録日 2024-04-13 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Transient interactions modulate the affinity of NF-kappa B transcription factors for DNA. Proc.Natl.Acad.Sci.USA, 121, 2024
9C6Q	Structure of V. cholerae monomeric DdmD bound with ssDNA 分子名称: Helicase/UvrB N-terminal domain-containing protein, ssDNA 著者 Shen, Z.F, Yang, X.Y, Fu, T.M. 登録日 2024-06-08 公開日 2024-08-21 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell, 187, 2024
9BF5	Structure of V. cholerae DdmD in complex with ssDNA 分子名称: Helicase/UvrB N-terminal domain-containing protein, ssDNA1, ssDNA2 著者 Shen, Z.F, Yang, X.Y, Fu, T.M. 登録日 2024-04-16 公開日 2024-09-04 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 DdmDE eliminates plasmid invasion by DNA-guided DNA targeting. Cell, 187, 2024
6HV9	S. cerevisiae CMG-Pol epsilon-DNA 分子名称: Cell division control protein 45, DNA (5'-D(*GP*CP*AP*GP*CP*CP*AP*CP*GP*CP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*GP*CP*GP*TP*GP*GP*CP*TP*GP*C)-3'), ... 著者 Abid Ali, F, Purkiss, A.G, Cheung, A, Costa, A. 登録日 2018-10-10 公開日 2018-12-12 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4.98 Å) 主引用文献 Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome. Nat Commun, 9, 2018
4KFC	Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA 分子名称: KDP operon transcriptional regulatory protein KdpE, Promoter DNA 著者 Kumar, S, Narayanan, A, Yernool, D.A. 登録日 2013-04-26 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
3E00	Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with GW9662, 9-cis Retinoic Acid and NCOA2 Peptide 分子名称: (9cis)-retinoic acid, 2-chloro-5-nitro-N-phenylbenzamide, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ... 著者 Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. 登録日 2008-07-30 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
3DZY	Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with Rosiglitazone, 9-cis Retinoic Acid and NCOA2 Peptide 分子名称: (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... 著者 Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. 登録日 2008-07-30 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
4KNY	Crystal structure of the response regulator KdpE complexed to DNA in an active-like conformation 分子名称: KDP operon transcriptional regulatory protein KdpE, Promoter DNA 著者 Kumar, S, Narayanan, A, Yernool, D.A. 登録日 2013-05-10 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.945 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
3DZU	Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide 分子名称: (9cis)-retinoic acid, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, DNA (5'-D(*DCP*DAP*DAP*DAP*DCP*DTP*DAP*DGP*DGP*DTP*DCP*DAP*DAP*DAP*DGP*DGP*DTP*DCP*DAP*DG)-3'), ... 著者 Chandra, V, Huang, P, Hamuro, Y, Raghuram, S, Wang, Y, Burris, T.P, Rastinejad, F. 登録日 2008-07-30 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 2008
5JLW	AntpHD with 15bp DNA duplex R-monothioated at Cytidine-8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7R)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... 著者 White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D. 登録日 2016-04-27 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.088 Å) 主引用文献 Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem, 17, 2016

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