PDB: 45817 件ウェブページステータス検索Chemie searchBIRD

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2PUB	CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES 分子名称: ADENINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR 著者 Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. 登録日 1997-10-04 公開日 1998-05-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
5T4W	Crystal structure of a DNA sequence d (CGTGAATTCACG) with DAPI 分子名称: 6-AMIDINE-2-(4-AMIDINO-PHENYL)INDOLE, DNA (5'-D(*CP*GP*TP*GP*AP*AP*TP*TP*CP*AP*CP*G)-3') 著者 Sbirkova, H, Schivachev, B. 登録日 2016-08-30 公開日 2017-08-23 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the DNA sequence d(CGTGAATTCACG)2 with DAPI. Acta Crystallogr F Struct Biol Commun, 73, 2017
2PUA	CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES 分子名称: 6-METHYLPURINE, DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PURINE REPRESSOR 著者 Schumacher, R.G, Choi, K.Y, Zalkin, H, Brennan, M.A. 登録日 1997-10-04 公開日 1998-05-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices. Science, 266, 1994
8VAR	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAQ	Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8VAL	Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Beta sliding clamp, ... 著者 Landeck, J.T, Kelch, B.A. 登録日 2023-12-11 公開日 2024-03-27 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication. J.Biol.Chem., 300, 2024
8CIZ	DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Mycoplanecin A. 分子名称: Beta sliding clamp, Mycoplanecin A 著者 Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. 登録日 2023-02-11 公開日 2023-11-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins. Nat Commun, 15, 2024
8CIY	DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Cyclohexyl-Griselimycin. 分子名称: ACETATE ION, Beta sliding clamp, CALCIUM ION, ... 著者 Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. 登録日 2023-02-11 公開日 2023-11-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins. Nat Commun, 15, 2024
8CIX	DNA-polymerase sliding clamp (DnaN) from Escherichia coli in complex with Griselimycin. 分子名称: ACETATE ION, Beta sliding clamp, CALCIUM ION, ... 著者 Fu, C, Liu, Y, Walt, C, Bader, C, Rasheed, S, Lukat, P, Neuber, M, Blankenfeldt, W, Kalinina, O, Mueller, R. 登録日 2023-02-11 公開日 2023-11-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins. Nat Commun, 15, 2024
5SWM	BACILLUS HALODURANS RNASE H MUTANT D132N IN COMPLEX WITH 12-MER FRNA/DNA HYBRID 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, DNA (12-MER), ... 著者 Pallan, P.S, Egli, M. 登録日 2016-08-08 公開日 2016-09-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'-FRNA:DNA Hybrid. Biochemistry, 55, 2016
4TQS	Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dCTP 分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ... 著者 Zhao, L. 登録日 2014-06-11 公開日 2015-01-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling. Biochemistry, 54, 2015
4TQR	Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dTTP 分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), ... 著者 Zhao, L. 登録日 2014-06-11 公開日 2015-01-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling. Biochemistry, 54, 2015
3M4O	RNA polymerase II elongation complex B 分子名称: DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Zhu, G, Huang, X, Lippard, S.J. 登録日 2010-03-11 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.57 Å) 主引用文献 X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
3N4M	E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ... 著者 Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L. 登録日 2010-05-21 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry, 59, 2020
8F6B	Crystal structure of murine PolG2 hexamer bound to DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*GP*GP*TP*AP*GP*GP*CP*GP*CP*CP*TP*AP*CP*CP*AP*G)-3'), ... 著者 Wojtaszek, J.L, Hoff, K.E, Williams, R.S. 登録日 2022-11-16 公開日 2023-08-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Res., 51, 2023
8F69	Crystal structure of murine PolG2 dimer bound to DNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Wojtaszek, J.L, Hoff, K.E, Williams, R.S. 登録日 2022-11-16 公開日 2023-08-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. Nucleic Acids Res., 51, 2023
5SXG	Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B 分子名称: 1,3-PROPANDIOL, DNA dC->dU-editing enzyme APOBEC-3B, IMIDAZOLE, ... 著者 Shi, K, Kurahashi, K, Aihara, H. 登録日 2016-08-09 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. Sci Rep, 7, 2017
3M3Y	RNA polymerase II elongation complex C 分子名称: DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Zhu, G, Huang, X, Lippard, S.J. 登録日 2010-03-10 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proc.Natl.Acad.Sci.USA, 107, 2010
5SXH	Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B 分子名称: 1,2-ETHANEDIOL, DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION 著者 Shi, K, Kurahashi, K, Aihara, H. 登録日 2016-08-09 公開日 2017-12-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B. Sci Rep, 7, 2017
6MR8	D276G DNA polymerase beta substrate complex with templating adenine and incoming Fapy-dGTP analog 分子名称: 1,2-ETHANEDIOL, 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol, CALCIUM ION, ... 著者 Freudenthal, B.D, Smith, M.R, Wilson, S.H, Beard, W.A. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 A guardian residue hinders insertion of a Fapy•dGTP analog by modulating the open-closed DNA polymerase transition. Nucleic Acids Res., 47, 2019
4KFC	Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA 分子名称: KDP operon transcriptional regulatory protein KdpE, Promoter DNA 著者 Kumar, S, Narayanan, A, Yernool, D.A. 登録日 2013-04-26 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nat Commun, 5, 2014
6NKV	Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with beta-gamma CHF analogue of dGTP 分子名称: 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKX	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with "hot-spot sequence" with dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKR	Ternary complex crystal structure of K289M variant of DNA polymerase Beta with dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020
6NKU	Ternary complex crystal structure of DNA polymerase Beta with "hot-spot sequence" with dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*AP*CP*AP*AP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2019-01-07 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Revealing an Internal Stabilization Deficiency in the DNA Polymerase beta K289M Cancer Variant through the Combined Use of Chemical Biology and X-ray Crystallography. Biochemistry, 59, 2020

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