4TQR

Ternary complex of Y-family DNA polymerase Dpo4 with (5'S)-8,5'-Cyclo-2'-deoxyguanosine and dTTP

Summary for 4TQR

Related4TQS
DescriptorDNA polymerase IV, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*T)-3'), DNA (5'-D(*TP*CP*AP*CP*(2LF)P*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... (8 entities in total)
Functional Keywordsy family dna polymerase, dna damage, cyclopurine, translesion synthesis, transferase-dna complex, transferase/dna
Biological sourceSulfolobus solfataricus
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Cellular locationCytoplasm  Q97W02
Total number of polymer chains3
Total molecular weight49253.03
Authors
Zhao, L. (deposition date: 2014-06-11, release date: 2015-01-14, Last modification date: 2015-02-04)
Primary citation
Xu, W.,Ouellette, A.M.,Wawrzak, Z.,Shriver, S.J.,Anderson, S.M.,Zhao, L.
Kinetic and Structural Mechanisms of (5'S)-8,5'-Cyclo-2'-deoxyguanosine-Induced DNA Replication Stalling.
Biochemistry, 54:639-651, 2015
PubMed: 25569151 (PDB entries with the same primary citation)
DOI: 10.1021/bi5014936
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.58 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20340.3%0.4%7.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
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PDB entries from 2020-08-05