PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4FLO	Crystal structure of Amylosucrase double mutant A289P-F290C from Neisseria polysaccharea 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Amylosucrase, GLYCEROL, ... 著者 Guerin, F, Champion, E, Moulis, C, Barbe, S, Tran, T.H, Morel, S, Descroix, K, Monsan, P, Mulard, L.A, Remaud-Simeon, M, Andre, I, Mourey, L, Tranier, S. 登録日 2012-06-15 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Applying pairwise combinations of amino Acid mutations for sorting out highly efficient glucosylation tools for chemo-enzymatic synthesis of bacterial oligosaccharides. J.Am.Chem.Soc., 134, 2012
7JRW	Phospholipase D engineered mutant bound to phosphatidic acid (5 day soak) 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... 著者 Vrielink, A, Samantha, A. 登録日 2020-08-13 公開日 2021-04-28 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
7JRV	Phospholipase D engineered mutant bound to phosphatidic acid (30 minute soak) 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... 著者 Vrielink, A, Samantha, A. 登録日 2020-08-13 公開日 2021-04-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
5EXL	FACTOR XIA IN COMPLEX WITH THE INHIBITOR 4-(aminomethyl)-~{N}-[(1~{S})-1-[4-(3-oxidanyl-1~{H}-indazol-5-yl)pyridin-2-yl]-2-phenyl-ethyl]cyclohexane-1-carboxamide 分子名称: 1,2-ETHANEDIOL, 4-(aminomethyl)-~{N}-[(1~{S})-1-[4-(3-oxidanyl-1~{H}-indazol-5-yl)pyridin-2-yl]-2-phenyl-ethyl]cyclohexane-1-carboxamide, Coagulation factor XIa light chain, ... 著者 Wei, A. 登録日 2015-11-23 公開日 2016-04-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group Bioorg.Med.Chem., 24, 2016
7JRU	Phospholipase D engineered mutant bound to phosphatidic acid (8 hour soak) 分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dibutanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... 著者 Vrielink, A, Samantha, A. 登録日 2020-08-13 公開日 2021-04-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478, 2021
5BVP	The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta 分子名称: CHLORIDE ION, Canakinumab Fab light-chain, Interleukin-1 beta, ... 著者 Rondeau, J.M. 登録日 2015-06-05 公開日 2015-09-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1 beta. Mabs, 7, 2015
3Q9Y	Crystal structure of human CK2 alpha in complex with Quinalizarin at pH 8.5 分子名称: 1,2,5,8-tetrahydroxyanthracene-9,10-dione, Casein kinase II subunit alpha, SULFATE ION 著者 Battistutta, R, Ranchio, A, Papinutto, E. 登録日 2011-01-10 公開日 2012-01-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2 To be Published
4J58	Human Cyclophilin D Complexed with an Inhibitor 分子名称: 1-(4-aminobenzyl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl]urea, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase F, ... 著者 Colliandre, L, Gelin, M, Bessin, Y, Guichou, J.F. 登録日 2013-02-08 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
2E6Q	Solution structure of the Ig-like domain (615-713) from human Obscurin-like protein 1 分子名称: Obscurin-like protein 1 著者 Qin, X.R, Suetake, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-12-28 公開日 2007-07-03 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Ig-like domain (615-713) from human Obscurin-like protein 1 To be published
4RDD	Co-crystal structure of SHP2 in complex with a Cefsulodin derivative 分子名称: 1-({(2R)-4-carboxy-2-[(R)-carboxy{[(2R)-2-phenyl-2-sulfoacetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyr idinium, Tyrosine-protein phosphatase non-receptor type 11 著者 Zhang, Z.Y, Yu, Z.H, He, R, Zhang, R.Y. 登録日 2014-09-18 公開日 2015-07-01 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. ACS Med Chem Lett, 6, 2015
5BV9	The Structure of Bacillus pumilus GH48 in complex with cellobiose 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Alahuhta, P.M, Lunin, V.V. 登録日 2015-06-04 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Strategies to reduce end-product inhibition in family 48 glycoside hydrolases. Proteins, 84, 2016
7JJN	Eubacterium rectale Amy13B (EUR_01860) 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Koropatkin, N.M, Cockburn, D.W, Cerqueira, F.M. 登録日 2020-07-27 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The structures of the GH13_36 amylases from Eubacterium rectale and Ruminococcus bromii reveal subsite architectures that favor maltose production Amylase, 4, 2020
4REF	Crystal Structure of TR3 LBD_L449W in complex with Molecule 2 分子名称: 1-(3,4,5-trihydroxyphenyl)hexan-1-one, GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Li, F.W, Cai, Q.X, Li, A.Z, Tian, X.Y, Wang, W.J, Yuan, W, Hou, P.P, Wu, Q, Lin, T.W. 登録日 2014-09-22 公開日 2015-09-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Induction of Autophagic Death in Cancer Cells by Agonizing TR3 and Attenuating Akt2 Activity Chem.Biol., 22, 2015
7GA2	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with POB0008 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Serine protease NS3, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.034 Å) 主引用文献 PanDDA analysis group deposition To Be Published
1T5B	Structural genomics, A protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase 分子名称: Acyl carrier protein phosphodiesterase, FLAVIN MONONUCLEOTIDE 著者 Zhang, R, Wu, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2004-05-03 公開日 2004-08-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 1.4 A crystal structure of a protein from Salmonella typhimurium similar to E. coli acyl carrier protein phosphodiesterase To be Published
7G9M	PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z44584886 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Serine protease NS3, ... 著者 Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2023-07-03 公開日 2023-07-26 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.541 Å) 主引用文献 PanDDA analysis group deposition To Be Published
1T46	STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE 分子名称: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PHOSPHATE ION 著者 Mol, C.D, Dougan, D.R, Schneider, T.R, Skene, R.J, Kraus, M.L, Scheibe, D.N, Snell, G.P, Zou, H, Sang, B.C, Wilson, K.P. 登録日 2004-04-28 公開日 2004-06-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J.Biol.Chem., 279, 2004
1WTU	TRANSCRIPTION FACTOR 1, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: TRANSCRIPTION FACTOR 1 著者 Jia, X, Grove, A, Ivancic, M, Hsu, V.L, Geiduschek, E.P, Kearns, D.R. 登録日 1996-07-29 公開日 1997-02-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution. J.Mol.Biol., 263, 1996
1WCU	CBM29_1, A Family 29 Carbohydrate Binding Module from Piromyces equi 分子名称: GLYCEROL, NON-CATALYTIC PROTEIN 1 著者 Flint, J, Bolam, D.N, Nurizzo, D, Taylor, E.J, Williamson, M.P, Walters, C, Davis, G.J, Gilbert, H.J. 登録日 2004-11-22 公開日 2005-03-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules J.Biol.Chem., 280, 2005
3R1I	Crystal structure of a short-chain type dehydrogenase/reductase from Mycobacterium marinum 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Short-chain type dehydrogenase/reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-03-10 公開日 2011-03-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
2GM8	TenA Homolog/Thi-4 Thiaminase complexed with product 4-amino-5-hydroxymethyl-2-methylpyrimidine 分子名称: 1,2-ETHANEDIOL, 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, tenA homolog/Thi-4 Thiaminase 著者 Sawaya, M.R, Chan, S, Han, G.W, Perry, L.J, Pashkov, I. 登録日 2006-04-06 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of a TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum To be Published
1TJK	Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe- Leu- Ser- Thr- Lys at 1.2 A resolution 分子名称: Phospholipase A2, SULFATE ION, synthetic peptide 著者 Singh, N, Jabeen, T, Somvanshi, R.K, Sharma, S, Perbandt, M, Dey, S, Betzel, C, Singh, T.P. 登録日 2004-06-06 公開日 2004-06-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of the complex formed between group II phospholipase A2 with a designed pentapeptide, Phe - Leu - Ser - Thr - Lys at 1.2 A resolution To be Published
3IA9	Crystal structure of a chemically synthesized [D25N]HIV-1 protease molecule complexed with MVT-101 reduced isostere inhibitor 分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, [D25N]HIV-1 protease 著者 Torbeev, V.Y, Kent, S.B.H. 登録日 2009-07-13 公開日 2011-07-27 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Hydrogen bonds at the protein-inhibitor interface in the HIV-1 protease / inhibitors complexes probed by total chemical synthesis and X-ray crystallography To be Published
4II2	Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg 分子名称: 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Olsen, S.K, Lima, C.D. 登録日 2012-12-19 公開日 2013-02-13 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer. Mol.Cell, 49, 2013
1X9I	Crystal structure of Crystal structure of phosphoglucose/phosphomannose phosphoglucose/phosphomannoseisomerase from Pyrobaculum aerophilum in complex with glucose 6-phosphate 分子名称: GLUCOSE-6-PHOSPHATE, GLYCEROL, glucose-6-phosphate isomerase 著者 Swan, M.K, Hansen, T, Schoenheit, P, Davies, C. 登録日 2004-08-21 公開日 2004-12-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Structural basis for phosphomannose isomerase activity in phosphoglucose isomerase from Pyrobaculum aerophilum: a subtle difference between distantly related enzymes. Biochemistry, 43, 2004

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