7JRW

Phospholipase D engineered mutant bound to phosphatidic acid (5 day soak)

Summary for 7JRW

Entry DOI	10.2210/pdb7jrw/pdb
Descriptor	Phospholipase D, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... (5 entities in total)
Functional Keywords	engineered mutant, pseudo-dimeric architecture, myo-inositol specificity, hydrolase
Biological source	Streptomyces antibioticus
Total number of polymer chains	1
Total formula weight	54601.61
Authors	Vrielink, A.,Samantha, A. (deposition date: 2020-08-13, release date: 2021-04-28, Last modification date: 2023-10-18)
Primary citation	Samantha, A.,Damnjanovic, J.,Iwasaki, Y.,Nakano, H.,Vrielink, A. Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation. Biochem.J., 478:1749-1767, 2021 Cited by PubMed: 33843991 DOI: 10.1042/BCJ20210117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation