PDB: 31171 件ウェブページステータス検索Chemie searchBIRD

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5U6F	Bacterial adhesin from Mobiluncus mulieris containing intramolecular disulfide, isopeptide, and ester bond cross-links (space group P21) 分子名称: LPXTG-motif cell wall anchor domain protein 著者 Paynter, J, Young, P.G, Squire, C.J. 登録日 2016-12-07 公開日 2018-06-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Domain structure and cross-linking in a giant adhesin from the Mobiluncus mulieris bacterium. Acta Crystallogr D Struct Biol, 79, 2023
5UAW	Structure of apo human PYCR-1 crystallized in space group P21212 分子名称: Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION 著者 Tanner, J.J. 登録日 2016-12-20 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1. J. Biol. Chem., 292, 2017
5UCW	Cytochrome P411 P-4 A82L A78V F263L amination catalyst 分子名称: NADPH-cytochrome P450 reductase 102A1V3, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhang, R.K, Buller, A.R, Arnold, F.H. 登録日 2016-12-22 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Enantioselective, intermolecular benzylic C-H amination catalysed by an engineered iron-haem enzyme. Nat Chem, 9, 2017
5UGH	Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366 分子名称: 2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine, S-adenosylmethionine synthase isoform type-2 著者 Kaiser, S.E, Feng, J, Stewart, A.E. 登録日 2017-01-08 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.062 Å) 主引用文献 Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat. Chem. Biol., 13, 2017
5UHK	Crystal structure of the core catalytic domain of Human O-GlcNAcase 分子名称: GLYCEROL, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain 著者 Klein, D.J, Elsen, N.L. 登録日 2017-01-11 公開日 2017-03-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Crystal structure of the core catalytic domain of human O-GlcNAcase and molecular basis of activity and inhibition To Be Published
5UHP	Crystal structure of the core catalytic domain of human O-GlcNAcase 分子名称: GLYCEROL, O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain 著者 Klein, D.J, Elsen, N.L. 登録日 2017-01-11 公開日 2017-03-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal structure of the core catalytic domain of human O-GlcNAcase and molecular basis of activity and inhibition To Be Published
5TY7	Crystal structure of wild-type S. aureus penicillin binding protein 4 (PBP4) in complex with nafcillin 分子名称: (2R,4S)-2-[(1R)-1-{[(2-ethoxynaphthalen-1-yl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4, SODIUM ION, ... 著者 Alexander, J.A.N, Strynadka, N.C.J. 登録日 2016-11-18 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.894 Å) 主引用文献 Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
5TYQ	Crystal structure of a holoenzyme methyltransferase involved in the biosynthesis of gentamicin 分子名称: MAGNESIUM ION, Putative gentamicin methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. 登録日 2016-11-21 公開日 2017-11-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.163 Å) 主引用文献 Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
5TZE	Crystal structure of S. aureus TarS in complex with UDP-GlcNAc 分子名称: Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... 著者 Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. 登録日 2016-11-21 公開日 2017-01-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
5TVU	Crystal structure of mitochondrial Hsp90 (TRAP1) with ATP in absence of Mg 分子名称: ADENOSINE-5'-TRIPHOSPHATE, TNF receptor-associated protein 1 著者 Elnatan, D, Betegon, M, Agard, D.A. 登録日 2016-11-10 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1. Elife, 6, 2017
5TWE	CTX-M-14 P167S:S70G mutant enzyme crystallized with ceftazidime 分子名称: ACYLATED CEFTAZIDIME, Beta-lactamase 著者 Patel, M, Stojanoski, V, Sankaran, B, Prasad, B.V.V, Palzkill, T. 登録日 2016-11-12 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation. Biochemistry, 56, 2017
5U04	Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase 分子名称: PHOSPHATE ION, ZINC ION, Zika Virus NS5 RdRp 著者 Godoy, A.S, Lima, G.M.A, Oliveira, K.I.Z, Torres, N.U, Maluf, F.V, Guido, R.V.C, Oliva, G. 登録日 2016-11-22 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase. Nat Commun, 8, 2017
5U0E	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-benzyl-2-sulfanylidene-1,3-thiazolidin-4-one, 1,2-ETHANEDIOL, Carbonic anhydrase 2, ... 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-23 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
5U0N	Crystal structure of a methyltransferase in complex with the substrate involved in the biosynthesis of gentamicin 分子名称: (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-xylopyranosyl)oxy]-2-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, MAGNESIUM ION, Putative gentamicin methyltransferase, ... 著者 Bury, P, Huang, F, Li, S, Sun, Y, Leadlay, P, Dias, M.V.B. 登録日 2016-11-25 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.115 Å) 主引用文献 Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
5TZK	Crystal structure of S. aureus TarS 1-349 in complex with UDP 分子名称: Glycosyl transferase, MANGANESE (II) ION, SULFATE ION, ... 著者 Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. 登録日 2016-11-21 公開日 2017-01-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
5TZP	Crystal structure of FPV039:Bik BH3 complex 分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bik, ... 著者 Anasir, M.I, Kvansakul, M. 登録日 2016-11-22 公開日 2017-05-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039. J. Biol. Chem., 292, 2017
5U0W	E. coli dihydropteroate synthase complexed with 9-methylguanine 分子名称: 9-METHYLGUANINE, ACETIC ACID, Dihydropteroate synthase 著者 Chhabra, S, Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2016-11-27 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase. Chemistry, 24, 2018
5U2H	Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Karasawa, A, Kawate, T. 登録日 2016-11-30 公開日 2017-01-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.903 Å) 主引用文献 Structural basis for subtype-specific inhibition of the P2X7 receptor. Elife, 5, 2016
5U96	Crystal structure of the coiled-coil domain from Listeria Innocua (Tetragonal Form) 分子名称: Putative integrase 著者 Gupta, K, Van Duyne, G.D, Sharp, R, Yuan, J.B. 登録日 2016-12-15 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Coiled-coil interactions mediate serine integrase directionality. Nucleic Acids Res., 45, 2017
5UAT	Structure of human PYCR-1 complexed with NADPH 分子名称: DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pyrroline-5-carboxylate reductase 1, ... 著者 Tanner, J.J. 登録日 2016-12-20 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1. J. Biol. Chem., 292, 2017
5UBB	Crystal structure of human alpha N-terminal protein methyltransferase 1B 分子名称: Alpha N-terminal protein methyltransferase 1B, S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION 著者 Dong, C, Zhu, L, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2016-12-20 公開日 2017-03-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An asparagine/glycine switch governs product specificity of human N-terminal methyltransferase NTMT2. Commun Biol, 1, 2018
5UBI	Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound PRPP 分子名称: 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ACETATE ION, ... 著者 Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J. 登録日 2016-12-20 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochem. J., 475, 2018
5UBH	Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound ATP 分子名称: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ATP phosphoribosyltransferase, ... 著者 Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J. 登録日 2016-12-20 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochem. J., 475, 2018
5TOO	Crystal structure of alkaline phosphatase PafA T79S, N100A, K162A, R164A mutant 分子名称: Alkaline phosphatase PafA, CHLORIDE ION, ZINC ION 著者 Lyubimov, A.Y, Sunden, F, AlSadhan, I, Herschlag, D. 登録日 2016-10-18 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.031 Å) 主引用文献 Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution. J. Biol. Chem., 292, 2017
5UC7	Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex 分子名称: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, D(-)-TARTARIC ACID 著者 Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2016-12-21 公開日 2017-01-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.835 Å) 主引用文献 Crystal structure of BioA / 7,8-diaminopelargonic acid aminotransferase / DAPA synthase from Citrobacter rodentium, PLP complex To Be Published

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