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PDB: 11 results
3H9V
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BU of 3h9v by Molmil
Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GADOLINIUM ATOM, P2X purinoceptor
Authors:Kawate, T, Michel, J.C, Gouaux, E.
Deposit date:2009-04-30
Release date:2009-07-28
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
3I5D
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BU of 3i5d by Molmil
Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor
Authors:Kawate, T, Michel, J.C, Gouaux, E.
Deposit date:2009-07-05
Release date:2009-08-04
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Crystal structure of the ATP-gated P2X(4) ion channel in the closed state.
Nature, 460, 2009
6VD7
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BU of 6vd7 by Molmil
Cryo-EM structure of Xenopus tropicalis pannexin 1 channel
Descriptor: Pannexin
Authors:Syrjanen, J.L, Michalski, M, Furukawa, H, Kawate, T.
Deposit date:2019-12-23
Release date:2020-02-26
Last modified:2020-04-15
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:The Cryo-EM structure of pannexin 1 reveals unique motifs for ion selection and inhibition.
Elife, 9, 2020
2A65
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BU of 2a65 by Molmil
Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Descriptor: CHLORIDE ION, LEUCINE, Na(+):neurotransmitter symporter (Snf family), ...
Authors:Yamashita, A, Singh, S.K, Kawate, T, Jin, Y, Gouaux, E.
Deposit date:2005-07-01
Release date:2005-08-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
Nature, 437, 2005
5U2H
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BU of 5u2h by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-30
Release date:2017-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.903 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1U
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BU of 5u1u by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-{(1R)-1-[N''-cyano-N'-(quinolin-5-yl)carbamimidamido]-2,2-dimethylpropyl}-2-(3,4-dimethoxyphenyl)acetamide, P2X purinoceptor
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-29
Release date:2017-01-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.604 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1Y
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BU of 5u1y by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N~2~-(3,4-difluorophenyl)-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}glycinamide, P2X purinoceptor
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-29
Release date:2017-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1X
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BU of 5u1x by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist JNJ47965567
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-{[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methyl}-2-(phenylsulfanyl)pyridine-3-carboxamide, ...
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-29
Release date:2017-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1L
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BU of 5u1l by Molmil
Crystal structure of the ATP-gated P2X7 ion channel in the closed, apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-28
Release date:2017-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1V
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BU of 5u1v by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A804598
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-cyano-N'-[(1R)-1-phenylethyl]-N''-quinolin-5-ylguanidine, ...
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-29
Release date:2017-01-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016
5U1W
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BU of 5u1w by Molmil
Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]-2-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]acetamide, ...
Authors:Karasawa, A, Kawate, T.
Deposit date:2016-11-29
Release date:2017-01-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:Structural basis for subtype-specific inhibition of the P2X7 receptor.
Elife, 5, 2016

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