5TYQ

Crystal structure of a holoenzyme methyltransferase involved in the biosynthesis of gentamicin

Summary for 5TYQ

Entry DOI	10.2210/pdb5tyq/pdb
Descriptor	Putative gentamicin methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	methyltransferase gentamicin biosynthesis sam, transferase
Biological source	Micromonospora echinospora
Total number of polymer chains	1
Total formula weight	37804.45
Authors	Bury, P.,Huang, F.,Leadlay, P.,Dias, M.V.B. (deposition date: 2016-11-21, release date: 2017-11-01, Last modification date: 2024-03-06)
Primary citation	Bury, P.D.S.,Huang, F.,Li, S.,Sun, Y.,Leadlay, P.F.,Dias, M.V.B. Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12:2779-2787, 2017 Cited by PubMed: 28876898 DOI: 10.1021/acschembio.7b00466 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.163 Å)

Structure validation