5TOO

Crystal structure of alkaline phosphatase PafA T79S, N100A, K162A, R164A mutant

Summary for 5TOO

Entry DOI	10.2210/pdb5too/pdb
Descriptor	Alkaline phosphatase PafA, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	alkaline phosphatase, phosphomonoesterase, pafa, weak phosphate binder, zinc bimetallo core, hydrolase
Biological source	Elizabethkingia meningoseptica
Total number of polymer chains	1
Total formula weight	61417.50
Authors	Lyubimov, A.Y.,Sunden, F.,AlSadhan, I.,Herschlag, D. (deposition date: 2016-10-18, release date: 2017-11-01, Last modification date: 2023-10-04)
Primary citation	Sunden, F.,AlSadhan, I.,Lyubimov, A.,Doukov, T.,Swan, J.,Herschlag, D. Differential catalytic promiscuity of the alkaline phosphatase superfamily bimetallo core reveals mechanistic features underlying enzyme evolution. J. Biol. Chem., 292:20960-20974, 2017 Cited by PubMed: 29070681 DOI: 10.1074/jbc.M117.788240 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.031 Å)

Structure validation