5UHK

Crystal structure of the core catalytic domain of Human O-GlcNAcase

Summary for 5UHK

• Entry DOI: 10.2210/pdb5uhk/pdb
• Related: 5UHL 5UHO 5UHP
• Descriptor: O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain, GLYCEROL, ... (4 entities in total)
• Functional Keywords: hydrolase, o-glcnacase, gh84, enzyme
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 3: Nucleus . Isoform 1: Cytoplasm : O60502 O60502
• Total number of polymer chains: 4
• Total formula weight: 117824.11

Authors

Klein, D.J.,Elsen, N.L. (deposition date: 2017-01-11, release date: 2017-03-29, Last modification date: 2024-03-06)

• Primary citation: Elsen, N.L.,Patel, S.B.,Ford, R.E.,Hall, D.L.,Hess, F.,Kandula, H.,Kornienko, M.,Lumb, K.J.,Reid, J.,Selnick, H.,Shipman, J.M.,Sharma, S.,Soisson, S.M.,Klein, D.J.; Crystal structure of the core catalytic domain of human O-GlcNAcase and molecular basis of activity and inhibition; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.97 Å)