5UHK
Crystal structure of the core catalytic domain of Human O-GlcNAcase
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | ASP174 |
| A | TYR219 |
| A | THR250 |
| A | TRP278 |
| A | ASN280 |
| A | GOL502 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | ASP285 |
| A | ASN313 |
| A | GOL501 |
| A | GLY67 |
| A | PHE68 |
| A | LYS98 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | GLY67 |
| C | ASP174 |
| C | TYR219 |
| C | TRP278 |
| C | ASN280 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01353, ECO:0000305|PubMed:16533067 |
| Chain | Residue | Details |
| A | ASP175 | |
| C | ASP175 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28939839, ECO:0007744|PDB:5VVT |
| Chain | Residue | Details |
| A | GLY67 | |
| C | ASP174 | |
| C | ASP175 | |
| C | TYR219 | |
| C | ASP285 | |
| C | ASN313 | |
| A | LYS98 | |
| A | ASP174 | |
| A | ASP175 | |
| A | TYR219 | |
| A | ASP285 | |
| A | ASN313 | |
| C | GLY67 | |
| C | LYS98 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER364 | |
| C | SER364 |
