5UHK
Crystal structure of the core catalytic domain of Human O-GlcNAcase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | O-GlcNAcase TIM-barrel domain | polymer | 345 | 39987.3 | 2 | UniProt (O60502) Pfam (PF07555) | Homo sapiens (Human) | OGA,Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Meningioma-expressed antigen 5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase,NCOAT |
| 2 | B, D (B, D) | O-GlcNAcase stalk domain | polymer | 163 | 18786.6 | 2 | UniProt (O60502) | Homo sapiens (Human) | OGA,Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Meningioma-expressed antigen 5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase,NCOAT |
| 3 | E, F, G (A, C) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I, J (A, B, C) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B, D: 544 - 705 (UniProt: O60502)
| PDB | External Database | Details |
|---|---|---|
| Met 543 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117547.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 117824.1 |
