PDB: 31171 件ウェブページステータス検索Chemie searchBIRD

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5TOA	Crystal Structure of ER beta bound to Estradiol 分子名称: ESTRADIOL, Estrogen receptor beta 著者 Textor, L, Nascimento, A.S, Polikarpov, I. 登録日 2016-10-17 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An alternative conformation of ER beta bound to estradiol reveals H12 in a stable antagonist position. Sci Rep, 7, 2017
5TGI	Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group P212121 分子名称: IncE, Sorting nexin-5 著者 Collins, B, Paul, B. 登録日 2016-09-28 公開日 2017-06-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structure of the SNX5 PX domain in complex with chlamydial protein IncE To Be Published
5TEZ	TCR F50 recgonizing M1-HLA-A2 分子名称: Beta-2-microglobulin, GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU, HLA class I histocompatibility antigen, ... 著者 Yang, X, Mariuzza, R.A. 登録日 2016-09-23 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope. J. Biol. Chem., 292, 2017
5TH7	Complex of SETD8 with MS453 分子名称: 1,2-ETHANEDIOL, N-(3-{[6,7-dimethoxy-2-(pyrrolidin-1-yl)quinazolin-4-yl]amino}propyl)propanamide, N-lysine methyltransferase KMT5A, ... 著者 Yu, W, Tempel, W, Babault, N, Ma, A, Butler, K.V, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2016-09-29 公開日 2016-11-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase. J. Med. Chem., 59, 2016
5THA	Gemin5 WD40 repeats in complex with a guanosyl moiety 分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, Gem-associated protein 5, UNKNOWN ATOM OR ION 著者 Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2016-09-29 公開日 2016-10-19 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
5THT	Crystal Structure of G303A HDAC8 in complex with M344 分子名称: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2016-09-30 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. Biochemistry, 55, 2016
5TG0	Crystal structure of the dimethylsulfoniopropionate (DMSP) lyase DddK complexed with iron and zinc 分子名称: FE (III) ION, ZINC ION, dimethylsulfoniopropionate lyase DddK 著者 Schnicker, N.J, Dey, M. 登録日 2016-09-27 公開日 2017-06-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Structural and Biochemical Insights into Dimethylsulfoniopropionate Cleavage by Cofactor-Bound DddK from the Prolific Marine Bacterium Pelagibacter. Biochemistry, 56, 2017
5TJ4	Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Pro306 fused to maltose binding protein 分子名称: SODIUM ION, Sugar ABC transporter substrate-binding protein,Gasdermin-B fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Chao, L.K, Herzberg, O. 登録日 2016-10-03 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TKF	Neurospora crassa polysaccharide monooxygenase 2 high mannosylation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... 著者 O'Dell, W.B, Meilleur, F. 登録日 2016-10-06 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction. Acta Crystallogr F Struct Biol Commun, 73, 2017
5TIJ	Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer) 分子名称: ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid, Gamma-enolase, MAGNESIUM ION 著者 Leonard, P.G, Muller, F.L. 登録日 2016-10-03 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.634 Å) 主引用文献 Eradication of ENO1-deleted Glioblastoma through Collateral Lethality Biorxiv, 2019
5TKG	Neurospora crassa polysaccharide monooxygenase 2 resting state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Lytic polysaccharide monooxygenase, ... 著者 O'Dell, W.B, Meilleur, F. 登録日 2016-10-06 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angew. Chem. Int. Ed. Engl., 56, 2017
5T3X	3.9 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074. 分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gristick, H.B, Bjorkman, P.J. 登録日 2016-08-26 公開日 2016-10-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site. Nat.Struct.Mol.Biol., 23, 2016
5TOQ	High resolution crystal structure of AAT 分子名称: Aspartate aminotransferase, cytoplasmic 著者 Mueser, T.C, Dajnowicz, S, Kovalevsky, A. 登録日 2016-10-18 公開日 2017-03-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase. J. Biol. Chem., 292, 2017
5U5N	The dimeric crystal structure of HTPA Reductase from Sellaginella moellendorffii 分子名称: CALCIUM ION, HTPA Reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Keown, J.R, Goldstone, D.C, Pearce, F.G. 登録日 2016-12-06 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly. Biochem. J., 475, 2018
5U6W	The crystal structure of 4-methylaminobenzoate-bound CYP199A4 分子名称: 4-(methylamino)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Coleman, T, Bruning, J.B, Bell, S.G. 登録日 2016-12-09 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.644 Å) 主引用文献 Cytochrome P450 CYP199A4 from Rhodopseudomonas palustris Catalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation Acs Catalysis, 8, 2018
5TWD	CTX-M-14 P167S apoenzyme 分子名称: Beta-lactamase 著者 Patel, M, Stojanoski, V, Sankaran, B, Prasad, B.V.V, Palzkill, T. 登録日 2016-11-12 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation. Biochemistry, 56, 2017
5TW4	Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftaroline 分子名称: CHLORIDE ION, Ceftaroline, bound form, ... 著者 Alexander, J.A.N, Strynadka, N.C.J. 登録日 2016-11-11 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance inStaphylococcus aureus. J. Biol. Chem., 2018
5TZ8	Crystal structure of S. aureus TarS 分子名称: Glycosyl transferase 著者 Worrall, L.J, Sobhanifar, S, King, D.T, Strynadka, N.C. 登録日 2016-11-21 公開日 2017-01-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid beta-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathog., 12, 2016
5TZQ	Crystal Structure of FPV039:Bmf BH3 complex 分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein FPV039, Bcl-2-modifying factor 著者 Anasir, M.I, Kvansakul, M. 登録日 2016-11-22 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039. J. Biol. Chem., 292, 2017
5U0K	C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA) 分子名称: Glutaminase liver isoform, mitochondrial 著者 Ferreira, I.M, Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. 登録日 2016-11-24 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.548 Å) 主引用文献 The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
5U0G	Identification of a New Zinc Binding Chemotype by Fragment Screening 分子名称: (5R)-5-[(2,4-dimethoxyphenyl)methyl]-1,3-thiazolidine-2,4-dione, 1,2-ETHANEDIOL, Carbonic anhydrase 2, ... 著者 Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. 登録日 2016-11-23 公開日 2017-08-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017
5U0Y	E. coli dihydropteroate synthase complexed with an 8-mercaptoguanine derivative: [(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]acetic acid 分子名称: 1,2-ETHANEDIOL, Dihydropteroate synthase, [(2-amino-6-oxo-6,9-dihydro-1H-purin-8-yl)sulfanyl]acetic acid 著者 Dennis, M.L, Peat, T.S, Swarbrick, J.D. 登録日 2016-11-27 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase. Chemistry, 24, 2018
5U18	Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the Geneticin 分子名称: GENETICIN, N-3'' methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. 登録日 2016-11-28 公開日 2017-11-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
5U1E	Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the kanamycin B 分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Putative gentamicin methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. 登録日 2016-11-28 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.213 Å) 主引用文献 Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
5TOJ	Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... 著者 Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. 登録日 2016-10-17 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017

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