5TJ4

Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Pro306 fused to maltose binding protein

Summary for 5TJ4

• Entry DOI: 10.2210/pdb5tj4/pdb
• Related: 5TIB 5TJ2
• Related PRD ID: PRD_900001
• Descriptor: Sugar ABC transporter substrate-binding protein,Gasdermin-B fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, SODIUM ION (3 entities in total)
• Functional Keywords: alpha helices, fusion protein, c-terminal domain, 1 snp, ligand binding protein
• Biological source: Escherichia coli, Homo sapiens (Human)
• Total number of polymer chains: 10
• Total formula weight: 617174.22

Authors

Chao, L.K.,Herzberg, O. (deposition date: 2016-10-03, release date: 2017-02-01, Last modification date: 2023-10-04)

• Primary citation: Chao, K.L.,Kulakova, L.,Herzberg, O.; Gene polymorphism linked to increased asthma and IBD risk alters gasdermin-B structure, a sulfatide and phosphoinositide binding protein.; Proc. Natl. Acad. Sci. U.S.A., 114:E1128-E1137, 2017; PubMed: 28154144; DOI: 10.1073/pnas.1616783114

Experimental method

X-RAY DIFFRACTION (3.5 Å)