PDB: 31171 件ウェブページステータス検索Chemie searchBIRD

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5TDQ	Crystal Structure of the GOLD domain of ACBD3 分子名称: Golgi resident protein GCP60 著者 McPhail, J.A, Burke, J.E. 登録日 2016-09-19 公開日 2016-11-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.493 Å) 主引用文献 The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase III beta , PI4KB, through ACBD3. Structure, 25, 2017
5TJE	Murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 and T cell receptor P14 分子名称: ALPHA CHAIN OF MURINE T CELL RECEPTOR p14, BETA CHAIN OF MURINE T CELL RECEPTOR p14, Beta-2-microglobulin, ... 著者 Achour, A, Sandalova, T, Allerbring, E, Popov, A. 登録日 2016-10-04 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant to be published
5TFT	Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex 分子名称: (4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hsu, M.H, Johnson, E.F. 登録日 2016-09-26 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
5TGJ	Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group I2 分子名称: IncE, Sorting nexin-5 著者 Collins, B, Paul, B. 登録日 2016-09-28 公開日 2017-10-11 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the SNX5 PX domain in complex with chlamydial protein IncE To Be Published
5TK5	Crystal structure of human 3HAO with iron bound in the active site 分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (III) ION, SULFATE ION 著者 Pidugu, L.S, Toth, E.A. 登録日 2016-10-06 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site. Acta Crystallogr D Struct Biol, 73, 2017
5TKY	Crystal structure of the co-translational Hsp70 chaperone Ssb in the ATP-bound, open conformation 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein 著者 Gumiero, A, Gese, G.V, Weyer, F.A, Lapouge, K, Sinning, I. 登録日 2016-10-10 公開日 2016-11-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun, 7, 2016
5THQ	Comprehensive Analysis of a Novel Ketoreductase for Pentangular Polyphenol Biosynthesis 分子名称: 3-oxoacyl-ACP reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Valentic, T.R, Tsai, S.C, Brady, S.F. 登録日 2016-09-30 公開日 2016-11-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Comprehensive Analysis of a Novel Ketoreductase for Pentangular Polyphenol Biosynthesis. ACS Chem. Biol., 11, 2016
5TIB	Gasdermin-B C-terminal domain containing the polymorphism residues Arg299:Ser306 fused to maltose binding protein 分子名称: ACETATE ION, SODIUM ION, Sugar ABC transporter substrate-binding protein,Gasdermin-B, ... 著者 Chao, K, Herzberg, O. 登録日 2016-10-01 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism Proc.Natl.Acad.Sci.Usa, 2017
5TKB	CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 4D IN COMPLEX WITH A TETRAFLUORANLINE COMPOUND 分子名称: ETHANOL, MAGNESIUM ION, N-[(2R)-2,3-dihydroxy-2-methylpropyl]-8-(methylamino)-6-[(2,3,5,6-tetrafluorophenyl)amino]imidazo[1,2-b]pyridazine-3-carboxamide, ... 著者 Sack, J.S. 登録日 2016-10-06 公開日 2016-12-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Identification of imidazo[1,2-b]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling. Medchemcomm, 8, 2017
5T7T	Galectin-8 N terminal domain in complex with LNT 分子名称: CHLORIDE ION, Galectin-8, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bohari, M.H, Yu, X, Blanchard, H. 登録日 2016-09-05 公開日 2017-01-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8. Sci Rep, 6, 2016
5T8P	Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to benzoxepin compound 2 分子名称: 6,7-dihydrothieno[4,5]oxepino[1,2-~{c}]pyridine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION 著者 Smith, M.A, McEwan, P.A. 登録日 2016-09-08 公開日 2017-01-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K). J. Med. Chem., 60, 2017
5T90	Structural mechanisms for alpha-conotoxin selectivity at the human alpha3beta4 nicotinic acetylcholine receptor 分子名称: Acetylcholine-binding protein, LsIA 著者 Abraham, N, Healy, M, Ragnarsson, L, Brust, A, Alewood, P, Lewis, R. 登録日 2016-09-08 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural mechanisms for alpha-conotoxin activity at the human alpha 3 beta 4 nicotinic acetylcholine receptor. Sci Rep, 7, 2017
5TDX	Resurrected Ancestral Hydroxynitrile Lyase from Flowering Plants 分子名称: Ancestral Hydroxynitrile Lyase 1, GLYCEROL 著者 Jones, B.J, Evans, R, Wilmot, C.M, Kazlauskas, R.J. 登録日 2016-09-20 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity. Plos One, 15, 2020
5TCW	ACC oxidase complex with nickel and acetate 分子名称: 1-aminocyclopropane-1-carboxylate oxidase 1, ACETATE ION, NICKEL (II) ION 著者 Gunawardana, D.M, Yosaatmadja, Y, Leung, I.K, Squire, C.J. 登録日 2016-09-15 公開日 2017-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 ACC oxidase complex with substrate 1-aminocyclopropane-1-carboxylic acid To Be Published
5THM	Esterase-6 from Drosophila melanogaster 分子名称: Esterase-6, N,N-dimethylboranamine 著者 Fraser, N.J, Jackson, C.J. 登録日 2016-09-29 公開日 2017-03-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis for the behavioral effects of the odorant degrading enzyme Esterase 6 in Drosophila. Sci Rep, 7, 2017
5THV	Crystal Structure of G305A HDAC8 in complex with M344 分子名称: 1,2-ETHANEDIOL, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2016-09-30 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.868 Å) 主引用文献 Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8. Biochemistry, 55, 2016
5TDE	TEV Cleaved Human ATP Citrate Lyase Bound to Citrate 分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ... 著者 Hu, J, Fraser, M.E. 登録日 2016-09-19 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallogr D Struct Biol, 73, 2017
5TEH	c-Src V281C kinase domain in complex with Rao-IV-156 分子名称: (2S)-3-[4-amino-7-(2-methoxyethyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyano-N-(propan-2-yl)propanamide, Proto-oncogene tyrosine-protein kinase Src 著者 Dieter, E.M, Merritt, E.A, Maly, D.J. 登録日 2016-09-21 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 A combined approach reveals a regulatory mechanism coupling Src's kinase activity, localization, and phosphotransferase-independent functions Mol.Cell, 2019
5TFN	CRYSTAL STRUCTURE OF THE ZIKA VIRUS NS2B-NS3 PROTEASE in super-open conformation 分子名称: NS2B-NS3 Protease CHIMERA,Genome polyprotein 著者 Aleshin, A.E, Bankston, L, Liddington, R.C. 登録日 2016-09-26 公開日 2017-10-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A novel conformation for the Zika virus NS2B-NS3 protease offers new insights into biological regulation and inhibitor design. To Be Published
5TG2	1.75 A resolution structure of Norovirus 3CL protease in complex with the a n-pentyl substituted macrocyclic inhibitor (17-mer) 分子名称: (4S,7S,17R)-7-(hydroxymethyl)-4-(2-methylpropyl)-17-pentyl-1-oxa-3,6,11-triazacycloheptadecane-2,5,10-trione, 3C-LIKE PROTEASE 著者 Lovell, S, Battaile, K.P, Mehzabeen, N, Damalanka, V.C, Kim, Y, Kankanamalage, A.C.G, Chang, K.-O, Groutas, W.C. 登録日 2016-09-27 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease. Eur J Med Chem, 127, 2016
5TKH	Neurospora crassa polysaccharide monooxygenase 2 ascorbate treated 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Lytic polysaccharide monooxygenase, ... 著者 O'Dell, W.B, Meilleur, F. 登録日 2016-10-06 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angew. Chem. Int. Ed. Engl., 56, 2017
5TJ3	Crystal structure of wild type alkaline phosphatase PafA to 1.7A resolution 分子名称: Alkaline phosphatase PafA, ZINC ION 著者 Lyubimov, A.Y, Sunden, F, Ressl, S, Herschlag, D. 登録日 2016-10-03 公開日 2016-11-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily. J.Am.Chem.Soc., 138, 2016
5TJD	Computer-based rational design of improved functionality for antibody catalysts toward organophosphorus compounds 分子名称: FAB A.17 L47K mutant HEAVY CHAIN, FAB A.17 L47K mutant Light Chain 著者 Chatziefthimiou, S, Stepanova, A, Smirnov, I, Gabibov, A, Wilmanns, M. 登録日 2016-10-04 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc.Natl.Acad.Sci.USA, 2020
5TCS	Crystal structure of a Dwarf Ndc80 Tetramer 分子名称: Kinetochore protein NDC80, Kinetochore protein NUF2, Kinetochore protein SPC24, ... 著者 Valverde, R, Harrison, S.C. 登録日 2016-09-15 公開日 2016-11-23 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2.8313 Å) 主引用文献 Conserved Tetramer Junction in the Kinetochore Ndc80 Complex. Cell Rep, 17, 2016
5TI8	Crystal Structure of an aspartate aminotransferase from Pseudomonas 分子名称: Aminotransferase, CALCIUM ION 著者 Peat, T.S, Newman, J. 登録日 2016-10-01 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Crystal structure of a putrescine aminotransferase from Pseudomonas sp. strain AAC. Acta Crystallogr F Struct Biol Commun, 73, 2017

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