7Q72
| Structure of Pla1 in complex with Red1 | 分子名称: | NURS complex subunit red1, Poly(A) polymerase pla1 | 著者 | Soni, K, Wild, K, Sinning, I. | 登録日 | 2021-11-09 | 公開日 | 2022-12-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
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7Q73
| Structure of Pla1 apo | 分子名称: | GLYCEROL, Poly(A) polymerase pla1 | 著者 | Soni, K, Wild, K, Sinning, I. | 登録日 | 2021-11-09 | 公開日 | 2022-12-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic insights into RNA surveillance by the canonical poly(A) polymerase Pla1 of the MTREC complex. Nat Commun, 14, 2023
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7Q74
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8G99
| Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase | 分子名称: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... | 著者 | Mullins, E.A, Chazin, W.J, Eichman, B.F. | 登録日 | 2023-02-21 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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7OMG
| Crystal structure of KOD DNA Polymerase in a ternary complex with an Uracil containing template | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ... | 著者 | Betz, K, Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2021-05-22 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
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7OMB
| Crystal structure of KOD DNA Polymerase in a ternary complex with a p/t duplex containing an extended 5' single stranded template overhang | 分子名称: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, ... | 著者 | Betz, K, Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2021-05-21 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
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3O2Q
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1L3S
| Crystal Structure of Bacillus DNA Polymerase I Fragment complexed to 9 base pairs of duplex DNA. | 分子名称: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3', DNA Polymerase I, ... | 著者 | Johnson, S.J, Taylor, J.S, Beese, L.S. | 登録日 | 2002-03-01 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1L3T
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 10 base pairs of duplex DNA following addition of a single dTTP residue | 分子名称: | 5'-D(*GP*AP*CP*G*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3', DNA Polymerase I, ... | 著者 | Johnson, S.J, Taylor, J.S, Beese, L.S. | 登録日 | 2002-03-01 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1L3V
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 15 base pairs of duplex DNA following addition of dTTP, dATP, dCTP, and dGTP residues. | 分子名称: | 5'-D(*GP*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*CP*GP*TP*C)-3', DNA Polymerase I, ... | 著者 | Johnson, S.J, Taylor, J.S, Beese, L.S. | 登録日 | 2002-03-01 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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7N4E
| Escherichia coli sigma 70-dependent paused transcription elongation complex | 分子名称: | 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Molodtsov, V, Su, M, Ebright, R.H. | 登録日 | 2021-06-04 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural and mechanistic basis of sigma-dependent transcriptional pausing. Proc.Natl.Acad.Sci.USA, 119, 2022
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5KI6
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1L3U
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue. | 分子名称: | 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', DNA Polymerase I, ... | 著者 | Johnson, S.J, Taylor, J.S, Beese, L.S. | 登録日 | 2002-03-01 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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1L5U
| Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 12 base pairs of duplex DNA following addition of a dTTP, a dATP, and a dCTP residue. | 分子名称: | 5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3', DNA Polymerase I, ... | 著者 | Johnson, S.J, Taylor, J.S, Beese, L.S. | 登録日 | 2002-03-08 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Processive DNA synthesis observed in a polymerase crystal suggests a
mechanism for the prevention of frameshift mutations Proc.Natl.Acad.Sci.USA, 100, 2003
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5C2Y
| Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription) | 分子名称: | GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ... | 著者 | Yogesha, S.D, Irani, S, Zhang, Y.J. | 登録日 | 2015-06-16 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase. Sci.Signal., 9, 2016
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8ASD
| Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION] | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), ... | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-19 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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1MUK
| reovirus lambda3 native structure | 分子名称: | MINOR CORE PROTEIN LAMBDA 3 | 著者 | Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. | 登録日 | 2002-09-24 | 公開日 | 2002-12-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | RNA Synthesis in a Cage-Structural Studies of Reovirus Polymerase lambda3 Cell(Cambridge,Mass.), 111, 2002
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2XC9
| BINARY COMPLEX OF SULFOLOBUS SOLFATARICUS DPO4 DNA POLYMERASE AND 1, N2-ETHENOGUANINE MODIFIED DNA, MAGNESIUM FORM | 分子名称: | 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*G)-3', 5'-D(*TP*CP*AP*CP*GNEP*GP*AP*AP*TP*CP*CP*TP*TP* CP*CP*CP*CP*C)-3', DNA POLYMERASE IV | 著者 | Irimia, A, Loukachevitch, L.V, Egli, M. | 登録日 | 2010-04-20 | 公開日 | 2010-09-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Metal Ion Dependence of the Active Site Conformation of the Trans-Lesion DNA Polymerase Dpo4 from Sulfolobus Solfataricus Acta Crystallogr.,Sect.F, 66, 2010
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5ZAK
| Cryo-EM structure of human Dicer and its complexes with a pre-miRNA substrate | 分子名称: | Endoribonuclease Dicer, RISC-loading complex subunit TARBP2 | 著者 | Liu, Z, Wang, J, Cheng, H, Ke, X, Sun, L, Zhang, Q.C, Wang, H.-W. | 登録日 | 2018-02-07 | 公開日 | 2018-05-09 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate. Cell, 173, 2018
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7KPX
| Structure of the yeast CKM | 分子名称: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | 登録日 | 2020-11-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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7KPV
| Structure of kinase and Central lobes of yeast CKM | 分子名称: | Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ... | 著者 | Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L. | 登録日 | 2020-11-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv, 7, 2021
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4DRW
| Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide | 分子名称: | Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein | 著者 | Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. | 登録日 | 2012-02-17 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure, 20, 2012
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7UO4
| SARS-CoV-2 replication-transcription complex bound to Remdesivir triphosphate, in a pre-catalytic state | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A. | 登録日 | 2022-04-12 | 公開日 | 2022-11-30 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023
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7UO9
| SARS-CoV-2 replication-transcription complex bound to UTP, in a pre-catalytic state | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A. | 登録日 | 2022-04-12 | 公開日 | 2022-11-30 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023
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7UOB
| SARS-CoV-2 replication-transcription complex bound to GTP, in a pre-catalytic state | 分子名称: | 3'-DEOXYURIDINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Malone, B.F, Perry, J.K, Appleby, T.C, Feng, J.Y, Campbell, E.A, Darst, S.A. | 登録日 | 2022-04-12 | 公開日 | 2022-11-30 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | 主引用文献 | Structural basis for substrate selection by the SARS-CoV-2 replicase. Nature, 614, 2023
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