8G99

Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase

Summary for 8G99

Entry DOI	10.2210/pdb8g99/pdb
EMDB information	29862 29864 29871 29872 29873 29886 29888 29889 29891
Descriptor	DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... (5 entities in total)
Functional Keywords	primase, dna polymerase, chimeric rna-dna primer, rna/dna hybrid, dna replication, dna synthesis, replication, transferase
Biological source	Xenopus laevis (African clawed frog) More
Total number of polymer chains	3
Total formula weight	256359.94
Authors	Mullins, E.A.,Chazin, W.J.,Eichman, B.F. (deposition date: 2023-02-21, release date: 2023-04-12, Last modification date: 2024-04-24)
Primary citation	Mullins, E.A.,Salay, L.E.,Durie, C.L.,Bradley, N.P.,Jackman, J.E.,Ohi, M.D.,Chazin, W.J.,Eichman, B.F. A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38491139 DOI: 10.1038/s41594-024-01227-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation