8G99
Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006260 | biological_process | DNA replication |
| A | 1902975 | biological_process | mitotic DNA replication initiation |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
| B | 0006260 | biological_process | DNA replication |
| B | 0006270 | biological_process | DNA replication initiation |
| C | 0003677 | molecular_function | DNA binding |
| C | 0005658 | cellular_component | alpha DNA polymerase:primase complex |
| C | 0006260 | biological_process | DNA replication |
| C | 0006269 | biological_process | DNA replication, synthesis of primer |
| C | 0006270 | biological_process | DNA replication initiation |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| C | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PROSITE/UniProt
| site_id | PS00116 |
| Number of Residues | 9 |
| Details | DNA_POLYMERASE_B DNA polymerase family B signature. YGDTDSIMI |
| Chain | Residue | Details |
| A | TYR996-ILE1004 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Zinc finger: {"description":"CysA-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 65 |
| Details | Region: {"description":"DNA-binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 26 |
| Details | Motif: {"description":"CysB motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P09884","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
