1L3U

Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 11 base pairs of duplex DNA following addition of a dTTP and a dATP residue.

Summary for 1L3U

• Entry DOI: 10.2210/pdb1l3u/pdb
• Related: 1L3S 1L3T 1L3V 1L5U
• Related PRD ID: PRD_900003
• Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3', 5'-D(*GP*AP*C*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', DNA Polymerase I, ... (7 entities in total)
• Functional Keywords: dna polymerase i, dna replication, klenow fragment, protein-dna complex, transferase-dna complex, transferase/dna
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 3
• Total formula weight: 75451.35

Authors

Johnson, S.J.,Taylor, J.S.,Beese, L.S. (deposition date: 2002-03-01, release date: 2003-03-25, Last modification date: 2023-08-16)

• Primary citation: Johnson, S.J.,Taylor, J.S.,Beese, L.S.; Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations; Proc.Natl.Acad.Sci.USA, 100:3895-3900, 2003; PubMed: 12649320; DOI: 10.1073/pnas.0630532100

Experimental method

X-RAY DIFFRACTION (1.8 Å)