2CJE
| THE CRYSTAL STRUCTURE OF A COMPLEX OF Leishmania major DUTPASE WITH SUBSTRATE ANALOGUE DUPNHP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-DIPHOSPHATE, DUTPASE, MAGNESIUM ION | 著者 | Moroz, O.V, Fogg, M.J, Gonzalez-Pacanowska, D, Wilson, K.S. | 登録日 | 2006-03-31 | 公開日 | 2007-04-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286, 2011
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6XIE
| PCSK9(deltaCRD) in complex with cyclic peptide 77 | 分子名称: | GLYCEROL, Peptide 77, Proprotein convertase subtilisin/kexin type 9 | 著者 | Orth, P. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design. J.Med.Chem., 63, 2020
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2CGI
| Siras structure of tetragonal lysozyme using derivative data collected at the high energy remote Holmium Kedge | 分子名称: | CHLORIDE ION, LYSOZYME C | 著者 | Jakoncic, J, Di Michiel, M, Zhong, Z, Honkimaki, V, Jouanneau, Y, Stojanoff, V. | 登録日 | 2006-03-07 | 公開日 | 2006-11-13 | 最終更新日 | 2019-01-23 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Anomalous Diffraction at Ultra-High Energy for Protein Crystallography. J.Appl.Crystallogr., 39, 2006
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2CIC
| THE CRYSTAL STRUCTURE OF A COMPLEX OF CAMPYLOBACTER JEJUNI DUTPASE WITH SUBSTRATE ANALOGUE DUPNHPP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDE HYDROLASE, MAGNESIUM ION | 著者 | Moroz, O.V, Harkiolaki, M, Gonzalez-Pacanowska, D, Wilson, K.S. | 登録日 | 2006-03-17 | 公開日 | 2007-03-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286, 2011
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8AG2
| Crystal structure of the BPTF bromodomain in complex with BI-7190 | 分子名称: | 5-[3-methoxy-4-[1-(4-methylpiperazin-1-yl)cyclopropyl]phenyl]-1,3,4-trimethyl-pyridin-2-one, Nucleosome-remodeling factor subunit BPTF | 著者 | Bader, G, Boettcher, J, Wolkerstorfer, B. | 登録日 | 2022-07-19 | 公開日 | 2022-08-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.025 Å) | 主引用文献 | Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. Chemmedchem, 18, 2023
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6XEO
| Structure of Mfd bound to dsDNA | 分子名称: | DNA (5'-D(P*AP*GP*GP*AP*TP*AP*CP*TP*TP*AP*CP*AP*GP*CP*CP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*GP*GP*CP*TP*GP*TP*AP*AP*GP*TP*AP*TP*CP*CP*T)-3'), Transcription-repair-coupling factor | 著者 | Brugger, C, Deaconescu, A. | 登録日 | 2020-06-12 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd. Nat Commun, 11, 2020
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6XID
| PCSK9(deltaCRD) in complex with cyclic peptide 51 | 分子名称: | GLYCEROL, Peptide 51, Proprotein convertase subtilisin/kexin type 9 | 著者 | Orth, P. | 登録日 | 2020-06-19 | 公開日 | 2020-11-18 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.482 Å) | 主引用文献 | Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design. J.Med.Chem., 63, 2020
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8HOB
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8HK7
| Structure of PKD2-F604P (Polycystin-2, TRPP2) with ML-SA1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione, CALCIUM ION, ... | 著者 | Chen, M.Y, Su, Q, Wang, Z.F, Yu, Y. | 登録日 | 2022-11-25 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands. Proc.Natl.Acad.Sci.USA, 121, 2024
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8AG1
| Crystal structure of a novel OX40 antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Novel OX40 antibody heavy chain, Novel OX40 antibody light chain, ... | 著者 | Gao, H, Zhou, A. | 登録日 | 2022-07-19 | 公開日 | 2023-07-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.303 Å) | 主引用文献 | Structural Basis of a Novel Agonistic Anti-OX40 Antibody. Biomolecules, 12, 2022
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6Z5V
| CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA IN CROTONASE FOLD AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE IN HAD FOLD | 分子名称: | 3-KETO-DECANOYL-COA, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Wierenga, R.K, Sridhar, S, Kiema, T.R. | 登録日 | 2020-05-27 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites. Acta Crystallogr D Struct Biol, 76, 2020
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2DY4
| Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol | 分子名称: | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase | 著者 | Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. | 登録日 | 2006-09-06 | 公開日 | 2007-01-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
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7YG5
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10GS
| HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH TER117 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, L-gamma-glutamyl-S-benzyl-N-[(S)-carboxy(phenyl)methyl]-L-cysteinamide | 著者 | Oakley, A, Parker, M. | 登録日 | 1997-08-14 | 公開日 | 1998-09-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution. J.Mol.Biol., 274, 1997
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6ZK0
| 1.47A human IMPase with ebselen | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Inositol monophosphatase 1, ... | 著者 | Bax, B.D, Fenn, G.D. | 登録日 | 2020-06-29 | 公開日 | 2020-09-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystallization and structure of ebselen bound to Cys141 of human inositol monophosphatase. Acta Crystallogr.,Sect.F, 76, 2020
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2BMQ
| The Crystal Structure of Nitrobenzene Dioxygenase in complex with nitrobenzene | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, FE (III) ION, ... | 著者 | Friemann, R, Ivkovic-Jensen, M.M, Lessner, D.J, Yu, C, Gibson, D.T, Parales, R.E, Eklund, H, Ramaswamy, S. | 登録日 | 2005-03-15 | 公開日 | 2005-05-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insight into the dioxygenation of nitroarene compounds: the crystal structure of nitrobenzene dioxygenase. J. Mol. Biol., 348, 2005
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2BWY
| Glu383Ala Escherichia coli Aminopeptidase P | 分子名称: | AMINOPEPTIDASE P, CITRATE ANION, MAGNESIUM ION, ... | 著者 | Graham, S.C, Guss, J.M. | 登録日 | 2005-07-19 | 公開日 | 2006-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Mutant Escherichia Coli Aminopeptidase P: Insights Into Substrate Recognition and the Mechanism of Catalysis. Biochemistry, 45, 2006
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2BMO
| The Crystal Structure of Nitrobenzene Dioxygenase | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, FE (III) ION, ... | 著者 | Friemann, R, Ivkovic-Jensen, M.M, Lessner, D.J, Yu, C, Gibson, D.T, Parales, R.E, Eklund, H, Ramaswamy, S. | 登録日 | 2005-03-15 | 公開日 | 2005-05-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural insight into the dioxygenation of nitroarene compounds: the crystal structure of nitrobenzene dioxygenase. J. Mol. Biol., 348, 2005
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2BWW
| His350Ala Escherichia coli Aminopeptidase P | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, AMINOPEPTIDASE P, CITRATE ANION, ... | 著者 | Graham, S.C, Guss, J.M. | 登録日 | 2005-07-19 | 公開日 | 2006-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Mutant Escherichia Coli Aminopeptidase P: Insights Into Substrate Recognition and the Mechanism of Catalysis. Biochemistry, 45, 2006
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2BWT
| Asp260Ala Escherichia coli Aminopeptidase P | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CITRATE ANION, MAGNESIUM ION, ... | 著者 | Graham, S.C, Guss, J.M. | 登録日 | 2005-07-19 | 公開日 | 2006-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Mutant Escherichia Coli Aminopeptidase P: Insights Into Substrate Recognition and the Mechanism of Catalysis. Biochemistry, 45, 2006
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2BMR
| The Crystal Structure of Nitrobenzene Dioxygenase in complex with 3- nitrotoluene | 分子名称: | 1,2-ETHANEDIOL, 3-NITROTOLUENE, ETHANOL, ... | 著者 | Friemann, R, Ivkovic-Jensen, M.M, Lessner, D.J, Yu, C, Gibson, D.T, Parales, R.E, Eklund, H, Ramaswamy, S. | 登録日 | 2005-03-15 | 公開日 | 2005-05-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insight into the dioxygenation of nitroarene compounds: the crystal structure of nitrobenzene dioxygenase. J. Mol. Biol., 348, 2005
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8JTS
| hOCT1 in complex with metformin in outward open conformation | 分子名称: | Metformin, Solute carrier family 22 member 1 | 著者 | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | 登録日 | 2023-06-22 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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6Z5O
| CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH COENZYME-A AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE | 分子名称: | COENZYME A, GLYCEROL, NICOTINAMIDE, ... | 著者 | Wierenga, R.K, Sridhar, S, Kiema, T.R. | 登録日 | 2020-05-27 | 公開日 | 2020-12-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites. Acta Crystallogr D Struct Biol, 76, 2020
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8JU0
| hOCT1 in complex with spironolactone in inward facing occluded conformation | 分子名称: | SPIRONOLACTONE, Solute carrier family 22 member 1 | 著者 | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | 登録日 | 2023-06-23 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTW
| hOCT1 in complex with nb5660 in inward facing partially open 1 conformation | 分子名称: | Solute carrier family 22 member 1, nanobody 56 | 著者 | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | 登録日 | 2023-06-22 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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