6Z5V

CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA IN CROTONASE FOLD AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE IN HAD FOLD

This is a non-PDB format compatible entry.

Summary for 6Z5V

• Entry DOI: 10.2210/pdb6z5v/pdb
• Related: 2X58
• Descriptor: Peroxisomal bifunctional enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-KETO-DECANOYL-COA, ... (6 entities in total)
• Functional Keywords: 3-ketodecanoyl-coa, beta-oxidation, peroxisome., oxidoreductase
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 2
• Total formula weight: 165537.43

Authors

Wierenga, R.K.,Sridhar, S.,Kiema, T.R. (deposition date: 2020-05-27, release date: 2020-12-09, Last modification date: 2024-01-24)

• Primary citation: Sridhar, S.,Schmitz, W.,Hiltunen, J.K.,Venkatesan, R.,Bergmann, U.,Kiema, T.R.,Wierenga, R.K.; Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites.; Acta Crystallogr D Struct Biol, 76:1256-1269, 2020; PubMed: 33263331; DOI: 10.1107/S2059798320013819

Experimental method

X-RAY DIFFRACTION (2.33 Å)