2CIC
THE CRYSTAL STRUCTURE OF A COMPLEX OF CAMPYLOBACTER JEJUNI DUTPASE WITH SUBSTRATE ANALOGUE DUPNHPP
Summary for 2CIC
Entry DOI | 10.2210/pdb2cic/pdb |
Related | 1W2Y 2CJE 2YAY 2YAZ 2YB0 |
Descriptor | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDE HYDROLASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | ligand complex, hydrolase, drug target, dutp pyrophosphatase |
Biological source | CAMPYLOBACTER JEJUNI |
Total number of polymer chains | 1 |
Total formula weight | 27567.51 |
Authors | Moroz, O.V.,Harkiolaki, M.,Gonzalez-Pacanowska, D.,Wilson, K.S. (deposition date: 2006-03-17, release date: 2007-03-27, Last modification date: 2023-12-13) |
Primary citation | Hemsworth, G.R.,Moroz, O.V.,Fogg, M.J.,Scott, B.,Bosch-Navarrete, C.,Gonzalez-Pacanowska, D.,Wilson, K.S. The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine. J.Biol.Chem., 286:16470-, 2011 Cited by PubMed: 21454646DOI: 10.1074/JBC.M111.224873 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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