PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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8U2S	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound, P21 form) 分子名称: 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase, CACODYLATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound, P21 form) To be published
8U2R	Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound) 分子名称: 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase, DI(HYDROXYETHYL)ETHER 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of Acetyl-coenzyme A synthetase from Leishmania infantum (Ethyl AMP bound) To be published
8U2Q	Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) To be published
8U2P	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-13 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) To be published
8U2O	Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor TCMDC-123995 分子名称: CHLORIDE ION, GLYCEROL, N-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamide, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-06 公開日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of Cdk-related protein kinase 6 (PK6) from Plasmodium falciparum in complex with inhibitor TCMDC-123995 To be published
8U2M	Structure of P450Blt from Micromonospora sp. MW-13 in Complex with Biarylitide 分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, ACETATE ION, Cytochrome P450-SU1, ... 著者 Hansen, M.H, Cryle, M.J. 登録日 2023-09-06 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural Insights into a Side Chain Cross-Linking Biarylitide P450 from RiPP Biosynthesis Acs Catalysis, 2024
8U2E	Bruton's tyrosine kinase in complex with N-[(2R)-1-[(3R)-3-(methylcarbamoyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl]-3-(3-methylphenyl)-1-oxopropan-2-yl]-1H-indazole-5-carboxamide 分子名称: (2S)-6-fluoro-5-[(3S)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-2-(4-methylpiperazine-1-carbonyl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Gajewski, S, Clifton, M.C. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. J.Med.Chem., 67, 2024
8U2D	Bruton's tyrosine kinase in complex with N-[(2R)-1-[(3R)-3-(methylcarbamoyl)-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-2-yl]-3-(3-methylphenyl)-1-oxopropan-2-yl]-1H-indazole-5-carboxamide 分子名称: (3R)-2-[N-(1H-indazole-5-carbonyl)-3-methyl-D-phenylalanyl]-N-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Gajewski, S, Clifton, M.C. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. J.Med.Chem., 67, 2024
8U2C	Gaussian mixture model based single particle refinement - ABC transporter (inhibitor-bound ABCG2 from EMPIAR-10374) 分子名称: 5D3 Fab heavy chain variable domain, 5D3 Fab light chain variable domain, Broad substrate specificity ATP-binding cassette transporter ABCG2, ... 著者 Chen, M, Pintilie, G. 登録日 2023-09-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8U2B	Cryo-EM structure of C.crescentus bNY30a pilus complex 分子名称: Flp family type IVb pilin 著者 Wang, Y, Zhang, J. 登録日 2023-09-05 公開日 2024-05-15 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus. Sci Adv, 10, 2024
8U29	Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ... 著者 Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2023-09-05 公開日 2023-12-06 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus. Cell Host Microbe, 31, 2023
8U28	Gaussian mixture model based single particle refinement - SARS (SARS-CoV-2 Spike Proteins on intact virions from EMPIAR-10492) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Chen, M, Pintilie, G. 登録日 2023-09-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8U27	Bcl-2-xL complexed with compound 35 分子名称: Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate 著者 Rizo, J, Pan, Y.-Z. 登録日 2023-09-05 公開日 2023-09-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol, 6, 2023
8U26	Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786) 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, M, Pintilie, G. 登録日 2023-09-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8U24	A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 9 分子名称: Green Fluorescent Protein Variant #9, ccGFP 9 著者 Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Engineering highly stable variants of Corynactis californica green fluorescent proteins. Protein Sci., 33, 2024
8U23	A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 8 分子名称: Green Fluorescent Protein Variant #8, ccGFP 8 著者 Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Engineering highly stable variants of Corynactis californica green fluorescent proteins. Protein Sci., 33, 2024
8U22	A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 7 分子名称: Green Fluorescent Protein Variant #7, ccGFP 7 著者 Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Engineering highly stable variants of Corynactis californica green fluorescent proteins. Protein Sci., 33, 2024
8U21	A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP E6 分子名称: Green Fluorescent Protein Variant E6, ccGFP E6 著者 Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Engineering highly stable variants of Corynactis californica green fluorescent proteins. Protein Sci., 33, 2024
8U20	A Highly Stable Variant of Corynactis Californica Green Fluorescent Protein, ccGFP 5 分子名称: Green Fluorescent Protein Variant #5, ccGFP 5 著者 Hung, L.-W, Terwilliger, T.C, Waldo, G, Nguyen, H.B. 登録日 2023-09-05 公開日 2024-01-31 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Engineering highly stable variants of Corynactis californica green fluorescent proteins. Protein Sci., 33, 2024
8U1X	The structure of the PP2A-B56Delta holoenzyme mutant - E197K 分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ... 著者 Wu, C.G, Xing, Y. 登録日 2023-09-04 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc.Natl.Acad.Sci.USA, 121, 2024
8U1W	Structure of Norovirus (Hu/GII.4/Sydney/NSW0514/2012/AU) protease bound to inhibitor NV-004 分子名称: ACETATE ION, GLYCEROL, Peptidase C37, ... 著者 Eruera, A.R, Campbell, A.C, Krause, K.L. 登録日 2023-09-03 公開日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease. Viruses, 15, 2023
8U1V	Structure of Norovirus (Hu/GII.4/Sydney/NSW0514/2012/AU) protease in the ligand-free state 分子名称: Peptidase C37 著者 Eruera, A.R, Campbell, A.C, Krause, K.L. 登録日 2023-09-03 公開日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease. Viruses, 15, 2023
8U1U	Structure of a class A GPCR/agonist complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Sun, D, Johnson, M, Masureel, M. 登録日 2023-09-02 公開日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14, 2023
8U1T	SARS-CoV-2 Envelope Protein Transmembrane Domain: Dimeric Structure Determined by Solid-State NMR 分子名称: Envelope small membrane protein 著者 Zhang, R, Qin, H, Prasad, R, Fu, R, Zhou, H.X, Cross, T. 登録日 2023-09-02 公開日 2023-11-15 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Dimeric Transmembrane Structure of the SARS-CoV-2 E Protein. Commun Biol, 6, 2023
8U1S	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ... 著者 Ferguson, J.A, Raghavan, S.S.R, Ward, A.B. 登録日 2023-09-02 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published

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