8TGU
 
 | | Cryo-EM structure of BG505 SOSIP trimer purified via Galanthus nivalis lectin chromatography | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope glycoprotein BG505 SOSIP, ... | | 著者 | Parsons, R.J, Pothula, K, Acharya, P. | | 登録日 | 2023-07-13 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.
Nat Commun, 15, 2024
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8TL3
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-d.01 FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP glycoprotein gp120, ... | | 著者 | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TL4
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-e.01 FAB | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | 著者 | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | 登録日 | 2023-07-26 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TWH
 | | Crystal structure of (GGGTT)3GGG G-quadruplex in complex with small molecule ligand RHPS4 | | 分子名称: | (GGGTT)3GGG DNA, 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, POTASSIUM ION | | 著者 | Yatsunyk, L.A, Martin, K.N, Lam, G. | | 登録日 | 2023-08-21 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal structure of (GGGTT)3GGG G-quadruplex in complex with small molecule ligand RHPS4
To be published
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8TUE
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8TYE
 | | Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Perrett, H.R, Brouwer, P.J.M, Ward, A.B. | | 登録日 | 2023-08-25 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Cell Rep, 43, 2024
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8TVT
 | | Structure of human Cysteine desulfurase Nfs1 with L-propargylglycine bound to active site PLP in complex with ISD11, Acp1 and ISCU2 | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | | 著者 | Cygler, M, Boniecki, M.T. | | 登録日 | 2023-08-18 | | 公開日 | 2024-09-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | D-Cysteine impairs tumor growth by inhibiting cysteine desulfurase NFS1
To Be Published
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8TYC
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8TRK
 | | Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist methyl blue | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4',4''-[methanetriyltris(4,1-phenyleneazanediyl)]tri(benzene-1-sulfonic acid), GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Oken, A.C, Ditter, I.A, Lisi, N.E, Krishnamurthy, I, McCarthy, A.E, Godsey, M.H, Mansoor, S.E. | | 登録日 | 2023-08-09 | | 公開日 | 2024-10-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | P2X 7 receptors exhibit at least three modes of allosteric antagonism.
Sci Adv, 10, 2024
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8UPL
 | | Cryo-EM structure of a Clockwise locked form of the Salmonella enterica Typhimurium flagellar C-ring, with C34 symmetry applied | | 分子名称: | Flagellar M-ring protein, Flagellar motor switch protein FliG, Flagellar motor switch protein FliM, ... | | 著者 | Johnson, S, Deme, J.C, Lea, S.M. | | 登録日 | 2023-10-22 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Structural basis of directional switching by the bacterial flagellum.
Nat Microbiol, 9, 2024
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8U5F
 | | Crystal Structure of Trypsinized Clostridium perfringens Enterotoxin | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Heat-labile enterotoxin B chain, ... | | 著者 | Kapoor, S, Ogbu, C.P, Vecchio, A.J. | | 登録日 | 2023-09-12 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin.
Toxins, 15, 2023
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8U8P
 | | S292F Streptomyces coelicolor Laccase | | 分子名称: | BORIC ACID, COPPER (II) ION, Copper oxidase, ... | | 著者 | Wang, J.-X, Lu, Y. | | 登録日 | 2023-09-18 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8U8Q
 | | V290N/S292F Streptomyces coelicolor Laccase | | 分子名称: | BORIC ACID, COPPER (II) ION, Copper oxidase, ... | | 著者 | Wang, J.-X, Lu, Y. | | 登録日 | 2023-09-18 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8U8T
 | | Y229F/V290N Streptomyces coelicolor Laccase | | 分子名称: | BORIC ACID, COPPER (II) ION, Copper oxidase, ... | | 著者 | Wang, J.-X, Lu, Y. | | 登録日 | 2023-09-18 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8U8R
 | | Y229F/V290N/S292F Streptomyces coelicolor Laccase | | 分子名称: | BORIC ACID, COPPER (II) ION, Copper oxidase, ... | | 著者 | Wang, J.-X, Lu, Y. | | 登録日 | 2023-09-18 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8U8S
 | | Y229F/S292F Streptomyces coelicolor Laccase | | 分子名称: | BORIC ACID, COPPER (II) ION, Copper oxidase, ... | | 著者 | Wang, J.-X, Lu, Y. | | 登録日 | 2023-09-18 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8UH4
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8UXL
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8UXM
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8UK9
 | | Structure of T4 Bacteriophage clamp loader mutant D110C bound to the T4 clamp, primer-template DNA, and ATP analog | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, DNA primer, ... | | 著者 | Marcus, K, Ghaffari-Kashani, S, Gee, C.L. | | 登録日 | 2023-10-12 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Nat.Struct.Mol.Biol., 31, 2024
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8UAE
 | | E. coli Sir2_HerA complex (12:6) with ATPgamaS | | 分子名称: | MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | | 登録日 | 2023-09-20 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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8UD9
 | | Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304 | | 分子名称: | (7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | Hsu, H.-C, Li, H. | | 登録日 | 2023-09-28 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.04 Å) | | 主引用文献 | Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.
Nat Commun, 14, 2023
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8UAF
 | | E. coli Sir2_HerA complex (12:6) bound with NAD+ | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | | 登録日 | 2023-09-20 | | 公開日 | 2023-12-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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6WKY
 | | Cryo-EM of Form 1 related peptide filament, 29-24-3 | | 分子名称: | peptide 29-24-3 | | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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7BL4
 | | in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Hilal, T, Nikolay, R, Spahn, C.M.T. | | 登録日 | 2021-01-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
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