Summary for 8UAE
Entry DOI | 10.2210/pdb8uae/pdb |
EMDB information | 42061 |
Descriptor | SIR2-like domain-containing protein, Nucleoside triphosphate hydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (5 entities in total) |
Functional Keywords | hera, sir2, nadase, atpase, anti-phage system, immune system |
Biological source | Escherichia coli More |
Total number of polymer chains | 18 |
Total formula weight | 981853.47 |
Authors | Shen, Z.F.,Lin, Q.P.,Fu, T.M. (deposition date: 2023-09-20, release date: 2023-12-27, Last modification date: 2024-03-27) |
Primary citation | Shen, Z.,Lin, Q.,Yang, X.Y.,Fosuah, E.,Fu, T.M. Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83:4586-4599.e5, 2023 Cited by PubMed: 38096827DOI: 10.1016/j.molcel.2023.11.007 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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