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3WRI
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BU of 3wri by Molmil
Crystal structure of P450cam
分子名称: CAMPHOR, Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of P450cam intermediate
To be Published
6YC2
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BU of 6yc2 by Molmil
Crystal structure of the light-driven sodium pump KR2 in the pentameric form at room temperature, pH 8.0
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ALANINE, EICOSANE, ...
著者Kovalev, K, Gushchin, I, Gordeliy, V.
登録日2020-03-18
公開日2020-04-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of light-driven sodium pumping.
Nat Commun, 11, 2020
3WRM
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BU of 3wrm by Molmil
Crystal structure of P450cam
分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ...
著者Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of P450cam intermedite
To be published
2Y98
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BU of 2y98 by Molmil
Structure of the mixed-function P450 MycG in complex with mycinamicin IV in P21212 space group
分子名称: CHLORIDE ION, GLYCEROL, MYCINAMICIN IV, ...
著者Li, S, Kells, P.M, Sherman, D.H, Podust, L.M.
登録日2011-02-12
公開日2012-02-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions.
J.Biol.Chem., 287, 2012
5CCI
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BU of 5cci by Molmil
Structure of the Mg2+-bound synaptotagmin-1 SNARE complex (short unit cell form)
分子名称: MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ...
著者Zhou, Q, Zhao, M, Lyubimov, A.Y, Uervirojnangkoorn, M, Weis, W.I, Brunger, A.T.
登録日2015-07-02
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.
Nature, 525, 2015
3NTY
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BU of 3nty by Molmil
Crystal structure of AKR1C1 in complex with NADP and 5-Phenyl,3-chlorosalicylic acid
分子名称: 5-chloro-4-hydroxybiphenyl-3-carboxylic acid, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Dhagat, U, El-Kabbani, O.
登録日2010-07-06
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Probing the inhibitor selectivity pocket of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis
Bioorg.Med.Chem.Lett., 21, 2011
6UPI
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BU of 6upi by Molmil
Crystal structure of Mycobacterium tuberculosis CYP121 bound with a hydroxylated intermediate of cYF-4-OMe
分子名称: (3S,6S)-3-{[4-(hydroxymethoxy)phenyl]methyl}-6-[(4-hydroxyphenyl)methyl]piperazine-2,5-dione, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE
著者Nguyen, R.C.D, Yang, Y, Liu, A.
登録日2019-10-17
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.808 Å)
主引用文献Substrate-Assisted Hydroxylation and O-Demethylation in the Peroxidase-like Cytochrome P450 Enzyme CYP121
Acs Catalysis, 10, 2020
3WRJ
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BU of 3wrj by Molmil
Crystal structure of P450cam
分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ...
著者Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of P450cam intermedite
to be published
3WVS
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BU of 3wvs by Molmil
Crystal Structure of Cytochrome P450revI
分子名称: (2E,4S,5S,6E,8E)-10-{(2R,3S,6S,8R,9S)-9-butyl-8-[(1E,3E)-4-carboxy-3-methylbuta-1,3-dien-1-yl]-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl}-5-hydroxy-4,8-dimethyldeca-2,6,8-trienoic acid, GLYCEROL, L(+)-TARTARIC ACID, ...
著者Nagano, S, Takahashi, S, Osada, H, Shiro, Y.
登録日2014-06-06
公開日2014-10-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.
J.Biol.Chem., 289, 2014
4YZ6
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BU of 4yz6 by Molmil
Crystal Structure of Myc3[44-238] from Arabidopsis in complex with Jaz1 peptide [200-221]
分子名称: Protein TIFY 10A, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J, Xu, H.E, Melcher, K, HE, S.Y.
登録日2015-03-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
3WRL
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BU of 3wrl by Molmil
Crystal structure of P450cam
分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ...
著者Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of P450cam intermedite
To be published
4Z5Q
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BU of 4z5q by Molmil
Crystal structure of the LnmZ cytochrome P450 hydroxylase from the leinamycin biosynthetic pathway of Streptomyces atroolivaceus S-140 at 1.8 A resolution
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Cytochrome P450 hydroxylase, ...
著者Ma, M, Lohman, J, Rudolf, J, Miller, M.D, Cao, H, Osipiuk, J, Joachimiak, A, Phillips Jr, G.N, Shen, B, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-04-02
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Crystal structure of the LnmZ cytochrome P450 hydroxylase from the leinamycin biosynthetic pathway of Streptomyces atroolivaceus S-140
To be Published
6B82
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BU of 6b82 by Molmil
Zebra Fish CYP-450 17A1 Mutant Abiraterone Complex
分子名称: ACETATE ION, Abiraterone, CHLORIDE ION, ...
著者Pallan, P.S, Egli, M.
登録日2017-10-05
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Inherent steroid 17 alpha ,20-lyase activity in defunct cytochrome P450 17A enzymes.
J. Biol. Chem., 293, 2018
3WRK
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BU of 3wrk by Molmil
Crystal structure of P450cam
分子名称: CAMPHOR, Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H.
登録日2014-02-25
公開日2015-03-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Structure of P450cam intermedite
To be Published
6VJX
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BU of 6vjx by Molmil
The crystal structure of 4-isobutylbenzoic acid-bound CYP199A4
分子名称: 4-(2-methylpropyl)benzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Doherty, Z.D, Bell, S.G, Bruning, J.
登録日2020-01-18
公開日2021-01-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.788 Å)
主引用文献The crystal structure of 4-isobutylbenzoic acid-bound CYP199A4
To Be Published
3W9C
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BU of 3w9c by Molmil
Crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin
分子名称: Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ...
著者Kikui, Y, Hiruma, Y, Hass, M.A, Koteishi, H, Ubbink, M, Nojiri, M.
登録日2013-04-03
公開日2013-08-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.
J.Mol.Biol., 425, 2013
3WEC
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BU of 3wec by Molmil
Structure of P450 RauA (CYP1050A1) complexed with a biosynthetic intermediate of aurachin RE
分子名称: 3-[(2E,6E,9R)-9-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-2-methylquinolin-4(1H)-one, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Yasutake, Y, Kitagawa, W, Tamura, T.
登録日2013-07-03
公開日2014-01-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structure of the quinoline N-hydroxylating cytochrome P450 RauA, an essential enzyme that confers antibiotic activity on aurachin alkaloids
Febs Lett., 588, 2014
2ZBZ
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BU of 2zbz by Molmil
Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84A mutant) in complex with 1,25-dihydroxyvitamin D3
分子名称: 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE
著者Sugimoto, H, Shinkyo, R, Hayashi, K, Yoneda, S, Yamada, M, Kamakura, M, Ikushiro, S, Shiro, Y, Sakaki, T.
登録日2007-10-30
公開日2008-04-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of CYP105A1 (P450SU-1) in Complex with 1alpha,25-Dihydroxyvitamin D3
Biochemistry, 47, 2008
3ZPI
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BU of 3zpi by Molmil
PikC D50N mutant in P21 space group
分子名称: 1,2-ETHANEDIOL, CYTOCHROME P450 HYDROXYLASE PIKC, FORMIC ACID, ...
著者Podust, L.M.
登録日2013-02-27
公開日2014-03-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Recognition of Synthetic Substrates by P450 Pikc
To be Published
2ZAW
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BU of 2zaw by Molmil
Crystal Structure of Ferric Cytochrome P450cam Reconstituted with 6-Methyl-6-depropionated Hemin
分子名称: 6-METHY-6-DEPROPIONATEHEMIN, CAMPHOR, CHLORIDE ION, ...
著者Harada, K, Sakurai, K, Shimada, H, Tsukihara, T, Hayashi, T.
登録日2007-10-11
公開日2008-01-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam
J.Am.Chem.Soc., 130, 2008
6BLD
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BU of 6bld by Molmil
Mycobacterium marinum cytochrome P450 CYP268A2 in complex with pseudoionone
分子名称: (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one, Cytochrome P450 268A2 Cyp268A2, PROTOPORPHYRIN IX CONTAINING FE
著者Child, S.A, Bruning, J.B, Bell, S.G.
登録日2017-11-09
公開日2018-01-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural and functional characterisation of the cytochrome P450 enzyme CYP268A2 from
Biochem. J., 475, 2018
7Q89
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BU of 7q89 by Molmil
OleP mutant G92W in complex with 6DEB
分子名称: 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ...
著者Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E.
登録日2021-11-10
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Biomolecules, 12, 2021
7Q6X
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BU of 7q6x by Molmil
OleP mutant S240Y in complex with 6DEB
分子名称: 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ...
著者Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E.
登録日2021-11-09
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Biomolecules, 12, 2021
7Q6R
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BU of 7q6r by Molmil
OleP mutant E89Y in complex with 6DEB
分子名称: 6-DEOXYERYTHRONOLIDE B, Cytochrome P-450, FORMIC ACID, ...
著者Savino, C, Montemiglio, L.C, Vallone, B, Exertier, C, Freda, I, Gugole, E.
登録日2021-11-09
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics.
Biomolecules, 12, 2021
7QGM
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BU of 7qgm by Molmil
Human CD73 (ecto 5'-nucleotidase) in complex with MRS4598 (a 3-methyl-CMPCP derivative, compound 16 in paper) in the closed state (crystal form III)
分子名称: 5'-nucleotidase, CALCIUM ION, ZINC ION, ...
著者Strater, N.
登録日2021-12-08
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-Activity Relationship of 3-Methylcytidine-5'-alpha , beta-methylenediphosphates as CD73 Inhibitors.
J.Med.Chem., 65, 2022

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件を2024-07-10に公開中

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