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8TI0
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ATP-1 state of Bcs1 (unsymmetrized)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
著者Zhan, J, Xia, D.
登録日2023-07-18
公開日2024-06-05
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
8THV
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BU of 8thv by Molmil
FARFAR-NMR ensemble of HIV-1 TAR with apical loop capturing ground and excited conformational states
分子名称: RNA (29-MER)
著者Roy, R, Geng, A, Shi, H, Merriman, D.K, Dethoff, E.A, Salmon, L, Al-Hashimi, H.M.
登録日2023-07-18
公開日2023-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble.
J.Am.Chem.Soc., 145, 2023
8THU
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BU of 8thu by Molmil
Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1
分子名称: DNA (145-MER), DNA (146-MER), Histone H2A.Z, ...
著者Abini-Agbomson, S, Armache, K.-J.
登録日2023-07-18
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.
Mol.Cell, 83, 2023
8THS
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BU of 8ths by Molmil
Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, LEA A69T
分子名称: DI(HYDROXYETHYL)ETHER, KAEDE-TYPE RED FLUORESCENT PROTEIN, LEA A69T, ...
著者Henderson, J.N, Mills, J.H.
登録日2023-07-17
公開日2023-11-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Capturing excited-state structural snapshots of evolutionary green-to-red photochromic fluorescent proteins.
Front Chem, 11, 2023
8THR
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BU of 8thr by Molmil
Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation
分子名称: (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter
著者Dalton, M.P, Coleman, J.A.
登録日2023-07-17
公開日2023-10-25
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural mechanisms for VMAT2 inhibition by tetrabenazine.
Elife, 12, 2024
8THP
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BU of 8thp by Molmil
PorX phosphatase null mutant (T271V)
分子名称: CALCIUM ION, GLYCEROL, Response regulator receiver protein
著者Saran, A, Zeytuni, N.
登録日2023-07-17
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献PorX phosphatase null mutant (T271V)
To Be Published
8THN
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BU of 8thn by Molmil
KcsA M96V mutant with Y78ester in High K+
分子名称: KcsA Fab Heavy Chain, KcsA Fab Light Chain, POTASSIUM ION, ...
著者Reddi, R, Valiyaveetil, F.I.
登録日2023-07-17
公開日2024-01-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds.
J.Biol.Chem., 300, 2023
8THM
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BU of 8thm by Molmil
Beta carbonic anhydrase from the carboxysome of Cyanobium PCC 7001
分子名称: 1,2-ETHANEDIOL, BICARBONATE ION, CARBON DIOXIDE, ...
著者Pulsford, S.B, Jackson, C.J.
登録日2023-07-17
公開日2023-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Alpha-cyanobacterial carbonic anhydrase is allosterically regulated by the Rubisco substrate Ribulose 1,5-bisphosphate (RuBP)
To Be Published
8THL
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BU of 8thl by Molmil
Cryo-EM structure of epinephrine-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8THK
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BU of 8thk by Molmil
Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric Gq-protein
分子名称: Endolysin,Alpha-1A adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Huang, X.Y.
登録日2023-07-17
公開日2023-08-16
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of agonist specificity of alpha 1A -adrenergic receptor.
Nat Commun, 14, 2023
8THJ
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BU of 8thj by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THI
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BU of 8thi by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THH
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BU of 8thh by Molmil
Cryo-EM structure of Nav1.7 with LTG
分子名称: (6M)-6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
著者Fan, X, Huang, J, Yan, N.
登録日2023-07-16
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Dual-pocket inhibition of Na v channels by the antiepileptic drug lamotrigine.
Proc.Natl.Acad.Sci.USA, 120, 2023
8THG
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BU of 8thg by Molmil
Cryo-EM structure of Nav1.7 with RLZ
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fan, X, Huang, J, Yan, N.
登録日2023-07-16
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Dual-pocket inhibition of Na v channels by the antiepileptic drug lamotrigine.
Proc.Natl.Acad.Sci.USA, 120, 2023
8THE
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BU of 8the by Molmil
Cryo-EM structure of Pseudomonas aeruginosa TonB-dependent transporter PhuR in complex with synthetic antibody and heme
分子名称: (2~{R},4~{R},5~{S},6~{S})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{R},4~{R},5~{S},6~{S})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{S})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Heme/hemoglobin uptake outer membrane receptor PhuR, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Knejski, P, Erramilli, S.K, Kossiakoff, A.A.
登録日2023-07-15
公開日2024-01-31
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding.
Structure, 32, 2024
8THD
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BU of 8thd by Molmil
Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to PCNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
著者Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
登録日2023-07-14
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
8THC
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BU of 8thc by Molmil
Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to a cracked PCNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
著者Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
登録日2023-07-14
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
8THB
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BU of 8thb by Molmil
Structure of the Saccharomyces cerevisiae PCNA clamp unloader Elg1-RFC complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
著者Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
登録日2023-07-14
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024
8THA
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BU of 8tha by Molmil
1TEL, non-compressed, double-helical crystal form
分子名称: Transcription factor ETV6,Activated CDC42 kinase 1
著者Smith, C.P, Wilson, E.W, Pedroza Romo, M.J, Averett, J.C, Moody, J.D.
登録日2023-07-14
公開日2023-08-23
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献1TEL, non-compressed, double-helical crystal form
To Be Published
8TH9
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BU of 8th9 by Molmil
Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA
分子名称: DIMETHYL SULFOXIDE, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), ...
著者Eckenroth, B.E, Doublie, S.
登録日2023-07-14
公開日2023-11-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural and biochemical insights into NEIL2's preference for abasic sites.
Nucleic Acids Res., 51, 2023
8TH8
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BU of 8th8 by Molmil
Linker domain of Nexin-dynein regulatory complex from Tetrahymena thermophila
分子名称: AAA family ATPase CDC48 subfamily protein, Calmodulin 7-2, Coiled-coil domain-containing protein 153, ...
著者Ghanaeian, A.G, Bui, K.H.
登録日2023-07-14
公開日2023-09-20
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Integrated modeling of the Nexin-dynein regulatory complex reveals its regulatory mechanism.
Nat Commun, 14, 2023
8TH7
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Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
分子名称: Caprin-1, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH6
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Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide
分子名称: 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-14
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH5
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BU of 8th5 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant
分子名称: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
著者Hughes, M.P, Taylor, J.P, Yang, Z.
登録日2023-07-13
公開日2024-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH4
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BU of 8th4 by Molmil
Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
分子名称: AT118-L Nanobody, BAG2 Anti-BRIL Fab Heavy Chain, BAG2 Anti-BRIL Fab Light Chain, ...
著者Skiba, M.A, Kruse, A.C.
登録日2023-07-13
公開日2024-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Antibodies expand the scope of angiotensin receptor pharmacology.
Nat.Chem.Biol., 2024

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件を2024-06-26に公開中

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