8THU

Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1

Summary for 8THU

• Entry DOI: 10.2210/pdb8thu/pdb
• EMDB information: 41272
• Descriptor: Histone H2A.Z, Histone H3.2, Histone H4, ... (6 entities in total)
• Functional Keywords: chromatin, histone h4 modification, methyltransferase, gene regulation, gene regulation-dna complex, gene regulation/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 198001.63

Authors

Abini-Agbomson, S.,Armache, K.-J. (deposition date: 2023-07-18, release date: 2023-09-06)

• Primary citation: Abini-Agbomson, S.,Gretarsson, K.,Shih, R.M.,Hsieh, L.,Lou, T.,De Ioannes, P.,Vasilyev, N.,Lee, R.,Wang, M.,Simon, M.D.,Armache, J.P.,Nudler, E.,Narlikar, G.,Liu, S.,Lu, C.,Armache, K.J.; Catalytic and non-catalytic mechanisms of histone H4 lysine 20 methyltransferase SUV420H1.; Mol.Cell, 83:2872-2883.e7, 2023; PubMed: 37595555; DOI: 10.1016/j.molcel.2023.07.020

Experimental method

ELECTRON MICROSCOPY (3.1 Å)