PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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4CEY	Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor NLD 分子名称: 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, SODIUM ION, VP1, ... 著者 De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I. 登録日 2013-11-12 公開日 2014-02-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules Nat.Struct.Mol.Biol., 21, 2014
1VKJ	Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, SULFATE ION, heparan sulfate (glucosamine) 3-O-sulfotransferase 1 著者 Thorp, S, Lee, K.A, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C. 登録日 2004-05-25 公開日 2004-06-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1 J.Biol.Chem., 279, 2004
1VQ4	The structure of the transition state analogue "DAA" bound to the large ribosomal subunit of Haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction. Mol.Cell, 20, 2005
8BM4	Hairpin adopted by modified oligonucleotide A32_mod found in the promoter of AUTS2 gene. 分子名称: A32_mod 著者 Novotny, A. 登録日 2022-11-10 公開日 2023-02-22 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural polymorphism driven by a register shift in a CGAG-rich region found in the promoter of the neurodevelopmental regulator AUTS2 gene. Nucleic Acids Res., 51, 2023
1VQO	The structure of CCPMN bound to the large ribosomal subunit haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU))-3', 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction. Mol.Cell, 20, 2005
1VJA	Urokinase Plasminogen Activator B-Chain-JT463 Complex 分子名称: N-(BENZYLSULFONYL)SERYL-N~1~-{4-[(Z)-AMINO(IMINO)METHYL]BENZYL}SERINAMIDE, SULFATE ION, plasminogen activator, ... 著者 Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. 登録日 2004-02-03 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
1VY6	Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Polikanov, Y.S, Steitz, T.A, Innis, C.A. 登録日 2014-05-13 公開日 2014-08-20 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
1VQL	The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction. Mol.Cell, 20, 2005
1M1K	Co-crystal structure of azithromycin bound to the 50S ribosomal subunit of Haloarcula marismortui 分子名称: 23S RRNA, 5S RRNA, AZITHROMYCIN, ... 著者 Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. 登録日 2002-06-19 公開日 2002-07-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol.Cell, 10, 2002
1VQN	The structure of CC-HPMN AND CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(LOF))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
1M8W	CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-19 RNA 分子名称: 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*GP*UP*CP*CP*AP*G)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', ... 著者 Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. 登録日 2002-07-26 公開日 2002-09-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
1W79	Crystal structure of the DD-transpeptidase-carboxypeptidase from Actinomadura R39 分子名称: D-alanyl-D-alanine carboxypeptidase, MAGNESIUM ION, SULFATE ION 著者 Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P. 登録日 2004-08-31 公開日 2005-06-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins. J. Biol. Chem., 280, 2005
1MFQ	Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle 分子名称: 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ... 著者 Kuglstatter, A, Oubridge, C, Nagai, K. 登録日 2002-08-13 公開日 2002-09-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Induced structural changes of 7SL RNA during the assembly of human signal recognition particle Nat.Struct.Biol., 9, 2002
4DED	Aurora A in complex with YL1-038-21 分子名称: 1,2-ETHANEDIOL, 2-({2-[(4-carbamoylphenyl)amino]pyrimidin-4-yl}amino)benzamide, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2012-01-20 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Development of o-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase Inhibitors. J.Med.Chem., 55, 2012
1VQ5	The structure of the transition state analogue "RAA" bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction. Mol.Cell, 20, 2005
1VQ6	The structure of c-hpmn and CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*(5AA)*(HFA))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
1M5P	Transition State Stabilization by a Catalytic RNA 分子名称: CALCIUM ION, RNA HAIRPIN RIBOZYME, RNA INHIBITOR SUBSTRATE, ... 著者 Rupert, P.B, Massey, A, Sigurdsson, S.T, Ferre-D'Amare, A.R. 登録日 2002-07-09 公開日 2002-10-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Transition state stabilization by a catalytic RNA Science, 298, 2002
1VPO	Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone 分子名称: TESTOSTERONE, anti-testosterone (heavy chain), anti-testosterone (light chain) 著者 Valjakka, J.M, Hemminki, A, Niemi, S, Soderlund, H, Takkinen, K, Rouvinen, J. 登録日 2004-11-15 公開日 2004-11-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS J.Biol.Chem., 277, 2002
1M8Z	Crystal Structure Of A Pumilio-Homology Domain 分子名称: BETA-MERCAPTOETHANOL, PUMILIO 1 著者 Wang, X, Zamore, P.D, Hall, T.M.T. 登録日 2002-07-26 公開日 2002-09-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a Pumilio homology domain. Mol.Cell, 7, 2001
1M8X	CRYSTAL STRUCTURE OF THE PUMILIO-HOMOLOGY DOMAIN FROM HUMAN PUMILIO1 IN COMPLEX WITH NRE1-14 RNA 分子名称: 5'-R(P*UP*GP*UP*AP*UP*AP*U)-3', 5'-R(P*UP*UP*GP*UP*AP*UP*AP*U)-3', Pumilio 1 著者 Wang, X, McLachlan, J, Zamore, P.D, Hall, T.M.T. 登録日 2002-07-26 公開日 2002-09-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 MODULAR RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY DOMAIN CELL(CAMBRIDGE,MASS.), 110, 2002
1MID	Non-specific lipid transfer protein 1 from barley in complex with L-alfa-lysophosphatidylcholine, Laudoyl 分子名称: [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM, nonspecific lipid-transfer protein 1 著者 Henriksen, A. 登録日 2002-08-23 公開日 2004-04-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Binding of L-alfa-lysophosphatidylcholine, lauroyl in the hydrophobic channel of barley lipid transfer protein To be Published
1VQ7	The structure of the transition state analogue "DCA" bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PAE)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA. Nature, 438, 2005
3SMR	Crystal structure of human WD repeat domain 5 with compound 分子名称: 1,2-ETHANEDIOL, 2-chloro-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ... 著者 Dong, A, Dombrovski, L, Wasney, G.A, Tempel, W, Senisterra, G, Bolshan, Y, Smil, D, Nguyen, K.T, Hajian, T, Poda, G, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Brown, P.J, Schapira, M, Arrowsmith, C.H, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2011-06-28 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem. J., 449, 2013
1VJ9	Urokinase Plasminogen Activator B-Chain-JT464 Complex 分子名称: N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... 著者 Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. 登録日 2004-02-03 公開日 2004-06-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
1VQP	The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui 分子名称: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ... 著者 Schmeing, T.M, Steitz, T.A. 登録日 2004-12-16 公開日 2005-11-29 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction. Mol.Cell, 20, 2005

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