1VPO

Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone

Replaces:  1L7S

Summary for 1VPO

• Entry DOI: 10.2210/pdb1vpo/pdb
• Related: 1L7T
• Descriptor: anti-testosterone (light chain), anti-testosterone (heavy chain), TESTOSTERONE, ... (4 entities in total)
• Functional Keywords: fab fragment, anti-steroid, testosterone complex, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 48024.03

Authors

Valjakka, J.M.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. (deposition date: 2004-11-15, release date: 2004-11-23, Last modification date: 2023-08-23)

• Primary citation: Valjakka, J.M.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J.; Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS; J.Biol.Chem., 277:44021-44027, 2002; PubMed: 12196551; DOI: 10.1074/jbc.M208392200

Experimental method

X-RAY DIFFRACTION (2.15 Å)