PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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2P93	Factor xa in complex with the inhibitor 5-chloro-N-(2-(4-(2-oxopyridin-1(2H)-yl)benzamido)ethyl)thiophene-2-carboxamide 分子名称: 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE, Factor Xa 著者 Chang, C.-H. 登録日 2007-03-23 公開日 2007-07-24 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa Bioorg.Med.Chem.Lett., 17, 2007
2P9T	Crystal Structure of Phosphoglycerate Kinase-2 bound to 3-phosphoglycerate 分子名称: 3-PHOSPHOGLYCERIC ACID, Phosphoglycerate kinase, testis specific 著者 Sawyer, G.M, Monzingo, A.F, Poteet, E.C, Robertus, J.D. 登録日 2007-03-26 公開日 2007-11-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus. Proteins, 71, 2007
2P98	E. coli methionine aminopeptidase monometalated with inhibitor YE7 分子名称: IMIDAZO[2,1-A]ISOQUINOLINE-2-CARBOHYDRAZIDE, MANGANESE (II) ION, Methionine aminopeptidase, ... 著者 Ye, Q. 登録日 2007-03-24 公開日 2007-11-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis. J.Med.Chem., 50, 2007
2P94	Factor xa in complex with the inhibitor 3-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclohexyl)-1H-indole-6-carboxamide 分子名称: 3-CHLORO-N-((1R,2S) -2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)CYCLOHEXYL)-1H-INDOLE-6-CARBOXAMIDE, Factor Xa 著者 Chang, C.-H. 登録日 2007-03-23 公開日 2007-07-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa Bioorg.Med.Chem.Lett., 17, 2007
2P9A	E. coli methionine aminopeptidase dimetalated with inhibitor YE6 分子名称: 5-(2-chlorophenyl)furan-2-carbohydrazide, MANGANESE (II) ION, Methionine aminopeptidase, ... 著者 Ye, Q. 登録日 2007-03-24 公開日 2007-11-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Inhibition of Monometalated Methionine Aminopeptidase: Inhibitor Discovery and Crystallographic Analysis. J.Med.Chem., 50, 2007
3SA0	Complex of ERK2 with norathyriol 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, norathyriol 著者 Kurinov, I, Malakhova, M. 登録日 2011-06-02 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5947 Å) 主引用文献 Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases. Cancer Res., 72, 2012
2PBW	Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex with the Partial agonist Domoic Acid at 2.5 A Resolution 分子名称: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, Glutamate receptor, ionotropic kainate 1 著者 Hald, H, Naur, P, Gajhede, M, Kastrup, J.S. 登録日 2007-03-29 公開日 2007-07-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. J.Biol.Chem., 282, 2007
3KTK	Structure of ClpP in complex with ADEP2 in triclinic crystal form 分子名称: ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 2 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
3KYF	Crystal structure of P4397 complexed with c-di-GMP 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Putative uncharacterized protein 著者 Ryu, K.S, Ko, J, Kim, H, Choi, B.S. 登録日 2009-12-06 公開日 2010-04-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of PP4397 Reveals the Molecular Basis for Different c-di-GMP Binding Modes by Pilz Domain Proteins. J.Mol.Biol., 398, 2010
3KZG	Crystal structure of an arginine 3rd transport system periplasmic binding protein from Legionella pneumophila 分子名称: Arginine 3rd transport system periplasmic binding protein 著者 Palani, K, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-12-08 公開日 2009-12-22 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structure of an arginine 3rd transport system periplasmic binding protein from Legionella pneumophila To be Published
2P7S	Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Amphinase-2, ... 著者 Singh, U.P. 登録日 2007-03-20 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enzymatic and Structural Characterisation of Amphinase, a Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes. J.Mol.Biol., 371, 2007
7OQH	CryoEM structure of the transcription termination factor Rho from Mycobacterium tuberculosis 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcription termination factor Rho 著者 Saridakis, E, Vishwakarma, R, Lai Kee Him, J, Martin, K, Simon, I, Cohen-Gonsaud, M, Coste, F, Bron, P, Margeat, E, Boudvillain, M. 登録日 2021-06-03 公開日 2022-02-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism. Commun Biol, 5, 2022
7ORJ	La Crosse virus polymerase at transcription capped RNA cleavage stage 分子名称: 5' capped RNA, ADENOSINE-5'-TRIPHOSPHATE, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORI	La Crosse virus polymerase at replication late-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORN	La Crosse virus polymerase at replication initiation stage 分子名称: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORL	La Crosse virus polymerase at transcription initiation stage 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORM	La Crosse virus polymerase at transcription early-elongation stage 分子名称: MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
7ORK	La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-D(*(GTG))-R(P*A)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
3KTH	Structure of ClpP from Bacillus subtilis in orthorombic crystal form 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
7ORO	La Crosse virus polymerase at replication early-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
3KTG	Structure of ClpP from Bacillus subtilis in monoclinic crystal form 分子名称: ATP-dependent Clp protease proteolytic subunit 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
3ZBF	Structure of Human ROS1 Kinase Domain in Complex with Crizotinib 分子名称: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS 著者 McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. 登録日 2012-11-08 公開日 2013-06-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Acquired Resistance to Crizotinib from a Mutation in Cd74-Ros1 N.Engl.J.Med., 368, 2013
2LGV	Rbx1 分子名称: E3 ubiquitin-protein ligase RBX1, ZINC ION 著者 Spratt, D.E, Shaw, G.S. 登録日 2011-08-02 公開日 2012-03-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Selective recruitment of an e2~ubiquitin complex by an e3 ubiquitin ligase. J.Biol.Chem., 287, 2012
3X2S	Crystal structure of pyrene-conjugated adenylate kinase 分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... 著者 Fujii, A, Sekiguchi, Y, Matsumura, H, Inoue, T, Chung, W.-S, Hirota, S, Matsuo, T. 登録日 2014-12-31 公開日 2015-04-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Excimer Emission Properties on Pyrene-Labeled Protein Surface: Correlation between Emission Spectra, Ring Stacking Modes, and Flexibilities of Pyrene Probes. Bioconjug.Chem., 26, 2015
2QHD	Crystal structure of ecarpholin S (ser49-PLA2) complexed with fatty acid 分子名称: LAURIC ACID, Phospholipase A2 著者 Zhou, X, Tan, T.C, Valiyaveettil, S, Go, M.L, Kini, R.M, Sivaraman, J. 登録日 2007-07-02 公開日 2007-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom Biophys.J., 95, 2008

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