7ORK

La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site

Summary for 7ORK

• Entry DOI: 10.2210/pdb7ork/pdb
• Related: 7ORJ
• EMDB information: 13039 13040
• Descriptor: RNA-directed RNA polymerase L, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3'), RNA (5'-R(P*AP*CP*UP*UP*GP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ... (8 entities in total)
• Functional Keywords: rna-dependent rna polymerase, viral protein
• Biological source: Bunyavirus La Crosse; More
• Total number of polymer chains: 4
• Total formula weight: 283657.21

Authors

Arragain, B.,Durieux Trouilleton, Q.,Baudin, F.,Cusack, S.,Schoehn, G.,Malet, H. (deposition date: 2021-06-06, release date: 2022-02-16, Last modification date: 2022-03-02)

• Primary citation: Arragain, B.,Durieux Trouilleton, Q.,Baudin, F.,Provaznik, J.,Azevedo, N.,Cusack, S.,Schoehn, G.,Malet, H.; Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.; Nat Commun, 13:902-902, 2022; PubMed: 35173159; DOI: 10.1038/s41467-022-28428-z

Experimental method

ELECTRON MICROSCOPY (3.1 Å)