7ORK
La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase L | polymer | 2276 | 264751.1 | 1 | UniProt (A5HC98) Pfam (PF15518) Pfam (PF04196) Pfam (PF21561) | Bunyavirus La Crosse | Protein L,Large structural protein,Replicase,Transcriptase |
| 2 | B (H) | RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3') | polymer | 17 | 5466.3 | 1 | La Crosse virus | ||
| 3 | C (T) | RNA (5'-R(P*AP*CP*UP*UP*GP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3') | polymer | 25 | 7882.7 | 1 | La Crosse virus | ||
| 4 | D (P) | RNA (5'-D(*(GTG))-R(P*A)-3') | polymer | 14 | 4936.0 | 1 | Homo sapiens | ||
| 5 | E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | G (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | H (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 8 | I, J, K (A, H, T) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A: 1 - 2263 (UniProt: A5HC98)
| PDB | External Database | Details |
|---|---|---|
| Lys 34 | His 34 | engineered mutation |
| Ser 1032 | - | insertion |
| Gly 1032 | - | insertion |
| Trp 1032 | - | insertion |
| Ser 1032 | - | insertion |
| His 1032 | - | insertion |
| Pro 1032 | - | insertion |
| Gln 1032 | - | insertion |
| Phe 1032 | - | insertion |
| Glu 1032 | - | insertion |
| Lys 1032 | - | insertion |
| Gly 1032 | - | insertion |
| Ser 1032 | - | insertion |
| Gly 1032 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 283036.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 621.2 | |
| All* | Total formula weight | 283657.2 |
