3SA0

Complex of ERK2 with norathyriol

Summary for 3SA0

• Entry DOI: 10.2210/pdb3sa0/pdb
• Related: 1TVO
• Descriptor: Mitogen-activated protein kinase 1, norathyriol, SULFATE ION, ... (4 entities in total)
• Functional Keywords: norathyriol complex, signal-regulated kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P28482
• Total number of polymer chains: 1
• Total formula weight: 42029.27

Authors

Kurinov, I.,Malakhova, M. (deposition date: 2011-06-02, release date: 2011-12-14, Last modification date: 2023-09-13)

• Primary citation: Li, J.,Malakhova, M.,Mottamal, M.,Reddy, K.,Kurinov, I.,Carper, A.,Langfald, A.,Oi, N.,Kim, M.O.,Zhu, F.,Sosa, C.P.,Zhou, K.,Bode, A.M.,Dong, Z.; Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases.; Cancer Res., 72:260-270, 2012; PubMed: 22084399; DOI: 10.1158/0008-5472.CAN-11-2596

Experimental method

X-RAY DIFFRACTION (1.5947 Å)