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1ZS4
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Structure of bacteriophage lambda cII protein in complex with DNA
分子名称: DNA - 27mer, Regulatory protein CII
著者Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A.
登録日2005-05-23
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
1ZS5
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Structure-based evaluation of selective and non-selective small molecules that block HIV-1 TAT and PCAF association
分子名称: (3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE, Histone acetyltransferase PCAF
著者Zeng, L, Godbole, S, Muller, M, Yan, S, Sanchez, R, Zhou, M.
登録日2005-05-23
公開日2006-05-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association
TO BE PUBLISHED
1ZS6
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structure of human nucleoside-diphosphate kinase 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase 3
著者Choe, J, Dimov, S, Arrowsmith, C, Edwards, A, Sundstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2005-05-23
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human nucleoside-diphosphate kinase 3
To be Published
1ZS7
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The structure of gene product APE0525 from Aeropyrum pernix
分子名称: PHOSPHATE ION, POTASSIUM ION, hypothetical protein APE0525
著者Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-23
公開日2005-07-05
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The structure of gene product APE0525 from Aeropyrum pernix
To be Published
1ZS8
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Crystal Structure of the Murine MHC Class Ib Molecule M10.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, histocompatibility 2, ...
著者Olson, R, Huey-Tubman, K.E, Dulac, C, Bjorkman, P.J.
登録日2005-07-22
公開日2005-07-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a pheromone receptor-associated MHC molecule with an open and empty groove.
Plos Biol., 3, 2005
1ZS9
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Crystal structure of human enolase-phosphatase E1
分子名称: E-1 ENZYME, MAGNESIUM ION
著者Wang, H, Pang, H, Bartlam, M, Rao, Z.
登録日2005-05-23
公開日2005-06-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human E1 Enzyme and its Complex with a Substrate Analog Reveals the Mechanism of its Phosphatase/Enolase
J.Mol.Biol., 348, 2005
1ZSA
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CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM
分子名称: CARBONIC ANHYDRASE II
著者Lesburg, C.A, Christianson, D.W.
登録日1996-01-09
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
Biochemistry, 35, 1996
1ZSB
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CARBONIC ANHYDRASE II MUTANT E117Q, TRANSITION STATE ANALOGUE ACETAZOLAMIDE
分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, ZINC ION
著者Lesburg, C.A, Christianson, D.W.
登録日1996-01-09
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
Biochemistry, 35, 1996
1ZSC
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CARBONIC ANHYDRASE II MUTANT E117Q, HOLO FORM
分子名称: CARBONIC ANHYDRASE II, ZINC ION
著者Lesburg, C.A, Christianson, D.W.
登録日1996-01-09
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II.
Biochemistry, 35, 1996
1ZSD
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Crystal Structure Of HLA-B*3501 Presenting an 11-Mer EBV Antigen EPLPQGQLTAY
分子名称: BZLF1 trans-activator protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Miles, J.J, Elhassen, D, Borg, N.A, Silins, S.L, Tynan, F.E, Burrows, J.M, Purcell, A.W, Kjer-Nielsen, L, Rossjohn, J, Burrows, S.R, McCluskey, J.
登録日2005-05-24
公開日2005-06-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献CTL Recognition of a Bulged Viral Peptide Involves Biased TCR Selection.
J.Immunol., 175, 2005
1ZSE
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RNA stemloop from bacteriophage Qbeta complexed with an N87S mutant MS2 Capsid
分子名称: Coat protein, RNA HAIRPIN
著者Horn, W.T, Tars, K, Grahn, E, Helgstrand, C, Baron, A.J, Lago, H, Adams, C.J, Peabody, D.S, Phillips, S.E.V, Stonehouse, N.J, Liljas, L, Stockley, P.G.
登録日2005-05-24
公開日2006-05-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis of RNA Binding Discrimination between Bacteriophages Qbeta and MS2
Structure, 14, 2006
1ZSF
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Crystal Structure of Complex of a Hydroxyethylamine Inhibitor with HIV-1 Protease at 2.0A Resolution
分子名称: N-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, PROTEASE RETROPEPSIN
著者Duskova, J, Skalova, T, Dohnalek, J, Petrokova, H, Hasek, J.
登録日2005-05-24
公開日2006-04-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1ZSG
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beta PIX-SH3 complexed with an atypical peptide from alpha-PAK
分子名称: Rho guanine nucleotide exchange factor 7, Serine/threonine-protein kinase PAK 1
著者Mott, H.R, Nietlispach, D, Evetts, K.A, Owen, D.
登録日2005-05-24
公開日2005-08-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Analysis of the SH3 Domain of beta-PIX and Its Interaction with alpha-p21 Activated Kinase (PAK)
Biochemistry, 44, 2005
1ZSH
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Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6)
分子名称: Beta-arrestin 1, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION
著者Milano, S.K, Kim, Y.M, Stefano, F.P, Benovic, J.L, Brenner, C.
登録日2005-05-24
公開日2006-01-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding
J.Biol.Chem., 281, 2006
1ZSJ
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in complex with N-(7-Carbamimidoyl-naphthalen-1-yl)-3-hydroxy-2-methyl-benzamide
分子名称: BICARBONATE ION, Coagulation factor XI, N-(7-CARBAMIMIDOYL-NAPHTHALEN-1-YL)-3-HYDROXY-2-METHYL-BENZAMIDE, ...
著者Guo, Z, Bannister, T, Noll, R, Jin, L, Rynkiewicz, M, Bibbins, F, Magee, S, Gorga, J, Babine, R.E, Strickler, J.E, Meyers, H.V, Abdel-Meguid, S.S.
登録日2005-05-24
公開日2006-05-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and Optimization of Potent and Selective Inhibitors for Human Factor XIa: Substituted Naphthamidine Series
To be Published
1ZSK
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Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 6-Carbamimidoyl-4-(3-hydroxy-2-methyl-benzoylamino)-naphthalene-2-carboxylic acid methyl ester
分子名称: 6-CARBAMIMIDOYL-4-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-NAPHTHALENE-2-CARBOXYLIC ACID METHYL ESTER, BICARBONATE ION, Coagulation factor XI, ...
著者Guo, Z, Bannister, T, Noll, R, Jin, L, Rynkiewicz, M, Bibbins, F, Magee, S, Gorga, J, Babine, R.E, Strickler, J.E, Meyers, H.V, Abdel-Meguid, S.S.
登録日2005-05-24
公開日2006-05-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and Optimization of Potent and Selective Inhibitors for Human Factor XIa: Substituted Naphthamidine Series
To be Published
1ZSL
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Factor XI complexed with a pyrimidinone inhibitor
分子名称: 2-(2-(3,4-DICHLOROPHENYL)-5-(ISOPROPYLAMINO)-6-OXOPYRIMIDIN-1(6H)-YL)-N-((S)-1-OXO-1-(THIAZOL-2-YL)-5-GUANIDINOPENTAN-2-YL)ACETAMIDE, Coagulation factor XI
著者Nagafuji, P, Jin, L, Rynkiewicz, M, Quinn, J, Bibbins, F, Meyers, H, Babine, R, Strickler, J, Abdel-Meguid, S.
登録日2005-05-24
公開日2006-05-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Pyrimidinone Inhibitors of a Thrombolytic Protease
To be Published
1ZSN
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Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives
分子名称: 5-CHLORO-2-(2-CHLORO-4-NITROPHENOXY)PHENOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, enoyl-acyl carrier reductase
著者Freundlich, J.S, Anderson, J.W, Sarantakis, D, Shieh, H.M, Yu, M, Lucumi, E, Kuo, M, Schiehser, G.A, Jacobus, D.P, Jacobs Jr, W.R, Fidock, D.A, Sacchettini, J.C.
登録日2005-05-24
公開日2006-05-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.992 Å)
主引用文献Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-Substituted triclosan derivatives.
Bioorg.Med.Chem.Lett., 15, 2005
1ZSO
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Hypothetical protein from plasmodium falciparum
分子名称: hypothetical protein
著者Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2005-05-24
公開日2005-06-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
1ZSP
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Contribution to Structure and Catalysis of Tyrosine 34 in Human Manganese Superoxide Dismutase
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial
著者Hearn, A.S, Perry, J.J, Cabelli, D.E, Tainer, J.A, Nick, H.S, Silverman, D.S.
登録日2005-05-24
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis.
Biochemistry, 48, 2009
1ZSQ
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Crystal Structure of MTMR2 in complex with phosphatidylinositol 3-phosphate
分子名称: 1,2-ETHANEDIOL, 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, Myotubularin-related protein 2
著者Begley, M.J, Taylor, G.S, Brock, M.A, Ghosh, P, Woods, V.L, Dixon, J.E.
登録日2005-05-25
公開日2006-01-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZSR
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Crystal structure of wild type HIV-1 protease (BRU isolate) with a hydroxyethylamine peptidomimetic inhibitor BOC-PHE-PSI[S-CH(OH)CH2NH]-PHE-GLU-PHE-NH2
分子名称: N-{(2S,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-4-phenylbutyl}-L-phenylalanyl-L-alpha-glutamyl-L-phenylalaninamide, PROTEASE RETROPEPSIN
著者Skalova, T, Dohnalek, J, Duskova, J, Petrokova, H, Hasek, J.
登録日2005-05-24
公開日2006-04-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 62, 2006
1ZSV
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Crystal structure of human NADP-dependent leukotriene B4 12-hydroxydehydrogenase
分子名称: CHLORIDE ION, NADP-dependent leukotriene B4 12-hydroxydehydrogenase
著者Turnbull, A.P, Johansson, C, Savitsky, P, Guo, K, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2005-05-25
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human NADP-dependent leukotriene B4 12-hydroxydehydrogenase
To be Published
1ZSW
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Crystal Structure of Bacillus cereus Metallo Protein from Glyoxalase family
分子名称: BETA-MERCAPTOETHANOL, Glyoxalase family protein, ZINC ION
著者Minasov, G, Shuvalova, L, Brunzelle, J.S, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-25
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Bacillus cereus Metallo Protein from Glyoxalase family
To be Published
1ZSX
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Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)
分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel beta-2 subunit
著者Wennerstrand, P, Johannsson, I, Ugochukwu, E, Kavanagh, K, Edwards, A, Arrowsmith, C, Williams, L, Sundstrom, M, Guo, K, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2005-05-25
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)
To be Published

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