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7XD8
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Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form)
分子名称: GLYCEROL, NS5, RNA (30-mer), ...
著者Wu, J, Wang, X, Gong, P.
登録日2022-03-26
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Proc.Natl.Acad.Sci.USA, 120, 2023
7X6S
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BU of 7x6s by Molmil
lymphocytic choriomeningitis virus RNA-dependent RNA polymerase (LCMV-L protein)
分子名称: MANGANESE (II) ION, RNA-directed RNA polymerase L
著者Liu, L, Lou, Z.
登録日2022-03-08
公開日2023-09-13
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7X6V
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BU of 7x6v by Molmil
lymphocytic choriomeningitis virus polymerase- Matrix Z Protein Complex (LCMV L-Z Complex)
分子名称: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
著者Liu, L, Lou, Z.
登録日2022-03-08
公開日2023-09-13
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7Z4O
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Influenza A/H7N9 polymerase core dimer with Pol II pSer5 CTD peptide mimic bound in site 2A
分子名称: MAGNESIUM ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Pflug, A.
登録日2022-03-04
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.412 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z43
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Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 1B and 2B
分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.123 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z42
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Influenza B polymerase with Pol II pSer5 CTD peptide mimic bound in site 2B
分子名称: DNA-directed RNA polymerase II subunit RPB1, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Drncova, P.
登録日2022-03-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.418 Å)
主引用文献Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD.
Plos Pathog., 18, 2022
7Z31
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Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z30
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Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11 terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z2Z
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Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z1L
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Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Girbig, M, Mueller, C.W.
登録日2022-02-24
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1N
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Structure of yeast RNA Polymerase III Delta C53-C37-C11
分子名称: CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC2, ...
著者Girbig, M, Mueller, C.W.
登録日2022-02-24
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1O
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Structure of yeast RNA Polymerase III PTC + NTPs
分子名称: CHAPSO, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Girbig, M, Mueller, C.W.
登録日2022-02-24
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z1M
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BU of 7z1m by Molmil
Structure of yeast RNA Polymerase III Elongation Complex (EC)
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, ...
著者Girbig, M, Mueller, C.W.
登録日2022-02-24
公開日2022-08-31
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
Cell Rep, 40, 2022
7Z0H
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BU of 7z0h by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-02-22
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7YZV
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BU of 7yzv by Molmil
Ryegrass mottle virus serine protease domain S159A mutant
分子名称: RNA-directed RNA polymerase
著者Kalnins, G.
登録日2022-02-21
公開日2022-03-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献VPg Impact on Ryegrass Mottle Virus Serine-like 3C Protease Proteolysis and Structure.
Int J Mol Sci, 24, 2023
7WUU
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BU of 7wuu by Molmil
CryoEM structure of loose sNS1 tetramer
分子名称: Core protein
著者Shu, B, Lok, S.M.
登録日2022-02-09
公開日2022-12-21
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUV
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CryoEM structure of sNS1 hexamer
分子名称: Core protein
著者Shu, B, Ooi, J.S.G, Lok, S.M.
登録日2022-02-09
公開日2022-12-21
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7WUT
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BU of 7wut by Molmil
CryoEM structure of stable sNS1 tetramer
分子名称: Core protein
著者Shu, B, Ooi, J.S.G, Lok, S.M.
登録日2022-02-09
公開日2022-12-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
7R1F
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BU of 7r1f by Molmil
Early transcription elongation state of influenza B polymerase backtracked due to double incoproation of nucleotide analogue T1106
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-02-02
公開日2022-12-28
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7R0E
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BU of 7r0e by Molmil
Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position
分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ...
著者Cusack, S, Kouba, T.
登録日2022-02-01
公開日2022-12-28
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
7TRD
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BU of 7trd by Molmil
Human telomerase catalytic core structure at 3.3 Angstrom
分子名称: Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7TRF
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Human telomerase catalytic core RNP with H2A/H2B
分子名称: Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7TRE
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Human telomerase catalytic core with shelterin protein TPP1
分子名称: Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7QXS
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BU of 7qxs by Molmil
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-27
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXA
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Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022

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