PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

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7R0E	Early transcription elongation state of influenza A/H7N9 polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-02-01 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
7TRD	Human telomerase catalytic core structure at 3.3 Angstrom 分子名称: Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ... 著者 Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. 登録日 2022-01-28 公開日 2022-04-20 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
7TRF	Human telomerase catalytic core RNP with H2A/H2B 分子名称: Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... 著者 Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. 登録日 2022-01-28 公開日 2022-04-20 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
7TRE	Human telomerase catalytic core with shelterin protein TPP1 分子名称: Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ... 著者 Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. 登録日 2022-01-28 公開日 2022-04-20 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
7QXS	Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains) 分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... 著者 Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. 登録日 2022-01-27 公開日 2022-03-02 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
7QXA	Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened) 分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... 著者 Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. 登録日 2022-01-26 公開日 2022-03-02 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
7QXB	Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map) 分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ... 著者 Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D. 登録日 2022-01-26 公開日 2022-03-02 最終更新日 2022-03-23 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Structural basis of human telomerase recruitment by TPP1-POT1. Science, 375, 2022
7WNJ	Crystal structure and Cap Binding analysis of the methyltransferase of Langat virus 分子名称: Core protein, S-ADENOSYL-L-HOMOCYSTEINE 著者 Chen, C, Ruixue, L. 登録日 2022-01-18 公開日 2023-01-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of NS5 Methyltransferase from Zika Virus To Be Published
7QTL	Influenza A/H7N9 polymerase elongation complex 分子名称: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ... 著者 Cusack, S, Kouba, T. 登録日 2022-01-14 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.48 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
7QSA	Structural basis on the interaction of Scribble PDZ domains with the Tick Born encephalitis virus (TBEV) NS5 protein 分子名称: Protein scribble homolog, RNA-directed RNA polymerase NS5 著者 Javorsky, A, Humbert, P.O, Kvansakul, M. 登録日 2022-01-13 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling. Biochem.J., 479, 2022
7QS9	Structural basis on the interaction of Scribble PDZ domains with the Tick Born encephalitis virus (TBEV) NS5 protein 分子名称: Protein scribble homolog, RNA-directed RNA polymerase NS5 著者 Javorsky, A, Humbert, P.O, Kvansakul, M. 登録日 2022-01-13 公開日 2022-08-31 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling. Biochem.J., 479, 2022
7THM	SARS-CoV-2 nsp12/7/8 complex with a native N-terminus nsp9 分子名称: MANGANESE (II) ION, Non-structural protein 7, Non-structural protein 8, ... 著者 Osinski, A, Tagliabracci, V.S, Chen, Z, Li, Y. 登録日 2022-01-11 公開日 2022-03-16 最終更新日 2024-01-17 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 The mechanism of RNA capping by SARS-CoV-2. Nature, 609, 2022
7WD4	Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design 分子名称: 1,2-ETHANEDIOL, GLYCEROL, NS3 helicase 著者 Wang, D.P, Wang, M.Y, Zhou, X, Wang, W.M, Cao, J.M. 登録日 2021-12-21 公開日 2023-01-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design To Be Published
7WBW	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3.5) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7WBV	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome 分子名称: DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7WBX	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. 登録日 2021-12-17 公開日 2023-07-05 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
7T5H	Structure of rabies virus phosphoprotein C-terminal domain, wild type 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Phosphoprotein, ... 著者 Zhan, J, Metcalfe, R.D, Gooley, P.R, Griffin, M.D.W. 登録日 2021-12-12 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein. J.Virol., 96, 2022
7T5G	Structure of rabies virus phosphoprotein C-terminal domain, S210E mutant 分子名称: Phosphoprotein, SULFATE ION 著者 Zhan, J, Metcalfe, R.D, Gooley, P.R, Griffin, M.D.W. 登録日 2021-12-12 公開日 2022-04-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Molecular Basis of Functional Effects of Phosphorylation of the C-Terminal Domain of the Rabies Virus P Protein. J.Virol., 96, 2022
7W9S	Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form) 分子名称: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... 著者 Wang, M, Gong, P. 登録日 2021-12-10 公開日 2022-11-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis. Nucleic Acids Res., 50, 2022
7QGH	Structure of the E. coli disome - collided 70S ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. 登録日 2021-12-08 公開日 2022-03-16 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (4.48 Å) 主引用文献 Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria. Nature, 603, 2022
7QG7	SARS-CoV-2 macrodomain Nsp3b bound to the remdesivir nucleoside GS-441524 分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, 1,2-ETHANEDIOL, Papain-like protease nsp3 著者 Wollenhaupt, J, Linhard, V, Sreeramulu, S, Weiss, M.S, Schwalbe, H. 登録日 2021-12-07 公開日 2021-12-15 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity. J.Mol.Biol., 434, 2022
7W82	Crystal structure of maize RDR2 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W84	CryoEM structure of apo form ZmRDR2 at 3.4 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W88	CryoEM structure of open form ZmRDR2 at 3.5 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7T17	Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment 分子名称: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ... 著者 Miller, A.S, Kuhn, R.J. 登録日 2021-12-01 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (5.26 Å) 主引用文献 A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization. Cell, 185, 2022

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