PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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3A1L	Crystal Structure of 11,11'-Dichlorochromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1) 分子名称: 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Makino, M, Sugimoto, H, Shiro, Y, Asamizu, S, Onaka, H, Nagano, S. 登録日 2009-04-09 公開日 2009-05-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules J.Am.Chem.Soc., 131, 2009
3G5N	Triple ligand occupancy crystal structure of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole 分子名称: 1-(biphenyl-4-ylmethyl)-1H-imidazole, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ... 著者 Gay, S.C, Sun, L, Maekawa, K, Halpert, J.R, Stout, C.D. 登録日 2009-02-05 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. Biochemistry, 48, 2009
3G93	Single ligand occupancy crystal structure of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole 分子名称: 1-(biphenyl-4-ylmethyl)-1H-imidazole, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Gay, S.C, Sun, L, Maekawa, K, Halpert, J.R, Stout, C.D. 登録日 2009-02-12 公開日 2009-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structures of cytochrome P450 2B4 in complex with the inhibitor 1-biphenyl-4-methyl-1H-imidazole: ligand-induced structural response through alpha-helical repositioning. Biochemistry, 48, 2009
3DBG	Crystal structure of Cytochrome P450 170A1 (CYP170A1) from Streptomyces coelicolor 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Zhao, B, Vassylyev, D.G, Waterman, M.R. 登録日 2008-05-31 公開日 2009-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site J.Biol.Chem., 284, 2009
3DGI	Crystal structure of F87A/T268A mutant of CYP BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Le Trong, I, Katayama, J.H, Totah, R.A, Stenkamp, R.E, Fox, E.P. 登録日 2008-06-13 公開日 2009-06-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Homolytic versus heterolytic dioxygen bond cleavage in cytochrome P450 BM3. To be Published
3HF2	Crystal structure of the I401P mutant of cytochrome P450 BM3 分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Yang, W, Whitehouse, C.J.C, Bell, S.G, Bartlam, M, Wong, L.L, Rao, Z. 登録日 2009-05-10 公開日 2009-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Highly Active Single-Mutation Variant of P450(BM3) (CYP102A1) Chembiochem, 10, 2009
2JJO	Structure of cytochrome P450 EryK in complex with its natural substrate erD 分子名称: CYTOCHROME P450 113A1, Erythromycin D, PROTOPORPHYRIN IX CONTAINING FE 著者 Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B. 登録日 2008-04-15 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284, 2009
2JJN	Structure of closed cytochrome P450 EryK 分子名称: CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B. 登録日 2008-04-15 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284, 2009
2JJP	Structure of cytochrome P450 EryK in complex with inhibitor ketoconazole (KC) 分子名称: 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Savino, C, Sciara, G, Miele, A.E, Kendrew, S.G, Vallone, B. 登録日 2008-04-15 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States. Biochemistry, 49, 2010
2WH8	Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines 分子名称: 5-AMINO-2-{4-[(4-AMINOPHENYL)SULFANYL]PHENYL}-1H-ISOINDOLE-1,3(2H)-DIONE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 130 著者 Podust, L.M, Ouellet, H, von Kries, J.P, Ortiz de Montellano, P.R. 登録日 2009-05-01 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J. Biol. Chem., 284, 2009
2WHF	Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines 分子名称: 1-(3-METHYLPHENYL)-1H-BENZIMIDAZOL-5-AMINE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 130 著者 Podust, L.M, Ouellet, H, von Kries, J.P, Ortiz de Montellano, P.R. 登録日 2009-05-04 公開日 2009-07-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J. Biol. Chem., 284, 2009
2WIO	Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea 分子名称: ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE 著者 Savino, C, Montemiglio, L.C, Sciara, G, Miele, A.E, Kedrew, S.G, Gianni, S, Vallone, B. 登録日 2009-05-14 公開日 2009-07-21 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate. J.Biol.Chem., 284, 2009
2WIV	Cytochrome-P450 XplA heme domain P21 分子名称: CYTOCHROME P450-LIKE PROTEIN XPLA, PROTOPORPHYRIN IX CONTAINING FE 著者 Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. 登録日 2009-05-18 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive. J.Biol.Chem., 284, 2009
2WIY	Cytochrome P450 XplA heme domain P21212 分子名称: 1,2-ETHANEDIOL, CYTOCHROME P450-LIKE PROTEIN XPLA, IMIDAZOLE, ... 著者 Sabbadin, F, Jackson, R, Bruce, N.C, Grogan, G. 登録日 2009-05-18 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The 1.5-A Structure of Xpla-Heme, an Unusual Cytochrome P450 Heme Domain that Catalyzes Reductive Biotransformation of Royal Demolition Explosive. J.Biol.Chem., 284, 2009
2ZQX	Cytochrome P450BSbeta cocrystallized with heptanoic acid 分子名称: Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. 登録日 2008-08-22 公開日 2009-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis. J.Biol.Inorg.Chem., 2010
2ZQJ	Substrate-Free Form of Cytochrome P450BSbeta 分子名称: Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. 登録日 2008-08-11 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis. J.Biol.Inorg.Chem., 2010
3EL3	Distinct Monooxygenase and Farnesene Synthase Active Sites in Cytochrome P450 170A1 分子名称: (3S,3aR,6S)-3,7,7,8-tetramethyl-2,3,4,5,6,7-hexahydro-1H-3a,6-methanoazulene, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 著者 Zhao, B, Waterman, M.R. 登録日 2008-09-19 公開日 2009-09-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site J.Biol.Chem., 284, 2009
2WM4	X-ray structure of Mycobacterium tuberculosis cytochrome P450 CYP124 in complex with phytanic acid 分子名称: (3R,7S,11S)-3,7,11,15-tetramethylhexadecanoic acid, CALCIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R. 登録日 2009-06-30 公開日 2009-10-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 106, 2009
2WM5	X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124 分子名称: PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 124 著者 Johnston, J.B, Kells, P.M, Podust, L.M, Ortiz de Montellano, P.R. 登録日 2009-06-30 公開日 2009-10-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A., 106, 2009
3G1Q	Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in ligand free state 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha-demethylase 著者 Lepesheva, G.I, Hargrove, T.Y, Harp, J, Wawrzak, Z, Waterman, M.R, Park, H. 登録日 2009-01-30 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections. J.Biol.Chem., 285, 2010
2ZUI	Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297N) 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. 登録日 2008-10-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant TO BE PUBLISHED
2ZUJ	Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant(D297L) 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. 登録日 2008-10-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant to be published
2ZUH	Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297A) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... 著者 Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. 登録日 2008-10-18 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant to be published
2WUZ	X-ray structure of CYP51 from Trypanosoma cruzi in complex with fluconazole in alternative conformation 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, LANOSTEROL 14-ALPHA-DEMETHYLASE, PUTATIVE, ... 著者 Chen, C.-K, Leung, S.S.F, Guilbert, C, Jacobson, M, McKerrow, J.H, Podust, L.M. 登録日 2009-10-11 公開日 2009-10-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural Characterization of Cyp51 from Trypanosoma Cruzi and Trypanosoma Brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole Plos Negl Trop Dis, 4, 2010
3K1O	Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole 分子名称: 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-6-O-{4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenyl}-1-(1H-1,2,4-triazol-1-yl)-D-erythro-hexitol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase 著者 Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. 登録日 2009-09-28 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi. J.Biol.Chem., 285, 2010

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