2WM5

X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124

Summary for 2WM5

• Entry DOI: 10.2210/pdb2wm5/pdb
• Related: 2WM4
• Descriptor: PUTATIVE CYTOCHROME P450 124, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: metal-binding, oxidoreductase, omega-hydroxylation, p450, iron, heme, fatty acid, monooxygenase
• Biological source: MYCOBACTERIUM TUBERCULOSIS
• Total number of polymer chains: 1
• Total formula weight: 49455.42

Authors

Johnston, J.B.,Kells, P.M.,Podust, L.M.,Ortiz de Montellano, P.R. (deposition date: 2009-06-30, release date: 2009-10-06, Last modification date: 2018-02-28)

• Primary citation: Johnston, J.B.,Kells, P.M.,Podust, L.M.,Ortiz de Montellano, P.R.; Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis.; Proc. Natl. Acad. Sci. U.S.A., 106:20687-20692, 2009; PubMed: 19933331; DOI: 10.1073/pnas.0907398106

Experimental method

X-RAY DIFFRACTION (1.5 Å)