2WIO

Structure of the histidine tagged, open cytochrome P450 Eryk from S. erythraea

Summary for 2WIO

Related2VRU 2JJN 2VRV 2JJP 2JJO
DescriptorERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywordssubstrate specificity, antibiotic biosynthesis, metal-binding, oxidoreductase, cytochrome p450, iron, heme, erythromicyn, monooxygenase
Biological sourceSACCHAROPOLYSPORA ERYTHRAEA
Total number of polymer chains1
Total molecular weight48134.86
Authors
Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kedrew, S.G.,Gianni, S.,Vallone, B. (deposition date: 2009-05-14, release date: 2009-07-21, Last modification date: 2011-07-13)
Primary citation
Savino, C.,Montemiglio, L.C.,Sciara, G.,Miele, A.E.,Kendrew, S.G.,Jemth, P.,Gianni, S.,Vallone, B.
Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284:29170-, 2009
PubMed: 19625248 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M109.003590
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2341307.3%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution